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Chemical Structure| 1236119-39-3 Chemical Structure| 1236119-39-3

Structure of 1236119-39-3

Chemical Structure| 1236119-39-3

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Product Details of [ 1236119-39-3 ]

CAS No. :1236119-39-3
Formula : C6H13NO2
M.W : 131.17
SMILES Code : C[C@@H](C(OC)=O)NCC
MDL No. :MFCD12783679

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Application In Synthesis of [ 1236119-39-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1236119-39-3 ]

[ 1236119-39-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 59237-53-5 ]
  • [ 1236119-39-3 ]
  • [ 1236119-40-6 ]
YieldReaction ConditionsOperation in experiment
66% at 90℃; for 1h;Inert atmosphere; closed vial; (S)-methyl 2-(ethylamino)propanoate (1.83 g, 14.0 mmol) was added to <strong>[59237-53-5]methyl 6-chloro-5-nitronicotinate</strong> (1.30 g, 6.00 mmol) and the reaction mixture was stirred in a closed vial at 90 C. for 1 h. It was cooled and diluted with EtOAc (25 mL). The resulting precipitate was filtered off, the filtrate was concentrated in vacuo and purified using flash column chromatography on silica gel (220 g SiO2, ethyl acetate in hexanes 0-50%) to afford the title compound as a yellow oil (1.23 g, 66%). [M+H] calc'd for C14H19N3O6, 326; found, 326.
 

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