Home Cart Sign in  
Chemical Structure| 1217501-27-3 Chemical Structure| 1217501-27-3

Structure of 1217501-27-3

Chemical Structure| 1217501-27-3

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1217501-27-3 ]

CAS No. :1217501-27-3
Formula : C9H15BN2O4
M.W : 226.04
SMILES Code : CC1=NN(C(OC(C)(C)C)=O)C(B(O)O)=C1
MDL No. :MFCD15143457

Safety of [ 1217501-27-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Computational Chemistry of [ 1217501-27-3 ] Show Less

Physicochemical Properties

Num. heavy atoms 16
Num. arom. heavy atoms 5
Fraction Csp3 0.56
Num. rotatable bonds 4
Num. H-bond acceptors 5.0
Num. H-bond donors 2.0
Molar Refractivity 59.22
TPSA ?

Topological Polar Surface Area: Calculated from
Ertl P. et al. 2000 J. Med. Chem.

84.58 Ų

Lipophilicity

Log Po/w (iLOGP)?

iLOGP: in-house physics-based method implemented from
Daina A et al. 2014 J. Chem. Inf. Model.

0.0
Log Po/w (XLOGP3)?

XLOGP3: Atomistic and knowledge-based method calculated by
XLOGP program, version 3.2.2, courtesy of CCBG, Shanghai Institute of Organic Chemistry

0.84
Log Po/w (WLOGP)?

WLOGP: Atomistic method implemented from
Wildman SA and Crippen GM. 1999 J. Chem. Inf. Model.

-0.35
Log Po/w (MLOGP)?

MLOGP: Topological method implemented from
Moriguchi I. et al. 1992 Chem. Pharm. Bull.
Moriguchi I. et al. 1994 Chem. Pharm. Bull.
Lipinski PA. et al. 2001 Adv. Drug. Deliv. Rev.

-0.25
Log Po/w (SILICOS-IT)?

SILICOS-IT: Hybrid fragmental/topological method calculated by
FILTER-IT program, version 1.0.2, courtesy of SILICOS-IT, http://www.silicos-it.com

-1.62
Consensus Log Po/w?

Consensus Log Po/w: Average of all five predictions

-0.28

Water Solubility

Log S (ESOL):?

ESOL: Topological method implemented from
Delaney JS. 2004 J. Chem. Inf. Model.

-1.74
Solubility 4.13 mg/ml ; 0.0183 mol/l
Class?

Solubility class: Log S scale
Insoluble < -10 < Poorly < -6 < Moderately < -4 < Soluble < -2 Very < 0 < Highly

Very soluble
Log S (Ali)?

Ali: Topological method implemented from
Ali J. et al. 2012 J. Chem. Inf. Model.

-2.2
Solubility 1.43 mg/ml ; 0.00632 mol/l
Class?

Solubility class: Log S scale
Insoluble < -10 < Poorly < -6 < Moderately < -4 < Soluble < -2 Very < 0 < Highly

Soluble
Log S (SILICOS-IT)?

SILICOS-IT: Fragmental method calculated by
FILTER-IT program, version 1.0.2, courtesy of SILICOS-IT, http://www.silicos-it.com

-0.6
Solubility 57.3 mg/ml ; 0.254 mol/l
Class?

Solubility class: Log S scale
Insoluble < -10 < Poorly < -6 < Moderately < -4 < Soluble < -2 Very < 0 < Highly

Soluble

Pharmacokinetics

GI absorption?

Gatrointestinal absorption: according to the white of the BOILED-Egg

High
BBB permeant?

BBB permeation: according to the yolk of the BOILED-Egg

No
P-gp substrate?

P-glycoprotein substrate: SVM model built on 1033 molecules (training set)
and tested on 415 molecules (test set)
10-fold CV: ACC=0.72 / AUC=0.77
External: ACC=0.88 / AUC=0.94

No
CYP1A2 inhibitor?

Cytochrome P450 1A2 inhibitor: SVM model built on 9145 molecules (training set)
and tested on 3000 molecules (test set)
10-fold CV: ACC=0.83 / AUC=0.90
External: ACC=0.84 / AUC=0.91

No
CYP2C19 inhibitor?

Cytochrome P450 2C19 inhibitor: SVM model built on 9272 molecules (training set)
and tested on 3000 molecules (test set)
10-fold CV: ACC=0.80 / AUC=0.86
External: ACC=0.80 / AUC=0.87

No
CYP2C9 inhibitor?

Cytochrome P450 2C9 inhibitor: SVM model built on 5940 molecules (training set)
and tested on 2075 molecules (test set)
10-fold CV: ACC=0.78 / AUC=0.85
External: ACC=0.71 / AUC=0.81

No
CYP2D6 inhibitor?

Cytochrome P450 2D6 inhibitor: SVM model built on 3664 molecules (training set)
and tested on 1068 molecules (test set)
10-fold CV: ACC=0.79 / AUC=0.85
External: ACC=0.81 / AUC=0.87

No
CYP3A4 inhibitor?

Cytochrome P450 3A4 inhibitor: SVM model built on 7518 molecules (training set)
and tested on 2579 molecules (test set)
10-fold CV: ACC=0.77 / AUC=0.85
External: ACC=0.78 / AUC=0.86

No
Log Kp (skin permeation)?

Skin permeation: QSPR model implemented from
Potts RO and Guy RH. 1992 Pharm. Res.

-7.08 cm/s

Druglikeness

Lipinski?

Lipinski (Pfizer) filter: implemented from
Lipinski CA. et al. 2001 Adv. Drug Deliv. Rev.
MW ≤ 500
MLOGP ≤ 4.15
N or O ≤ 10
NH or OH ≤ 5

0.0
Ghose?

Ghose filter: implemented from
Ghose AK. et al. 1999 J. Comb. Chem.
160 ≤ MW ≤ 480
-0.4 ≤ WLOGP ≤ 5.6
40 ≤ MR ≤ 130
20 ≤ atoms ≤ 70

None
Veber?

Veber (GSK) filter: implemented from
Veber DF. et al. 2002 J. Med. Chem.
Rotatable bonds ≤ 10
TPSA ≤ 140

0.0
Egan?

Egan (Pharmacia) filter: implemented from
Egan WJ. et al. 2000 J. Med. Chem.
WLOGP ≤ 5.88
TPSA ≤ 131.6

0.0
Muegge?

Muegge (Bayer) filter: implemented from
Muegge I. et al. 2001 J. Med. Chem.
200 ≤ MW ≤ 600
-2 ≤ XLOGP ≤ 5
TPSA ≤ 150
Num. rings ≤ 7
Num. carbon > 4
Num. heteroatoms > 1
Num. rotatable bonds ≤ 15
H-bond acc. ≤ 10
H-bond don. ≤ 5

0.0
Bioavailability Score?

Abbott Bioavailability Score: Probability of F > 10% in rat
implemented from
Martin YC. 2005 J. Med. Chem.

0.55

Medicinal Chemistry

PAINS?

Pan Assay Interference Structures: implemented from
Baell JB. & Holloway GA. 2010 J. Med. Chem.

0.0 alert
Brenk?

Structural Alert: implemented from
Brenk R. et al. 2008 ChemMedChem

1.0 alert: heavy_metal
Leadlikeness?

Leadlikeness: implemented from
Teague SJ. 1999 Angew. Chem. Int. Ed.
250 ≤ MW ≤ 350
XLOGP ≤ 3.5
Num. rotatable bonds ≤ 7

No; 1 violation:MW<1.0
Synthetic accessibility?

Synthetic accessibility score: from 1 (very easy) to 10 (very difficult)
based on 1024 fragmental contributions (FP2) modulated by size and complexity penaties,
trained on 12'782'590 molecules and tested on 40 external molecules (r2 = 0.94)

2.91

Application In Synthesis of [ 1217501-27-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1217501-27-3 ]

[ 1217501-27-3 ] Synthesis Path-Downstream   1~10

  • 1
  • [ 1217501-27-3 ]
  • [ 1356000-09-3 ]
  • [ 1356001-98-3 ]
YieldReaction ConditionsOperation in experiment
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; In 1,4-dioxane; water; at 110℃; for 1h;microwave irradiation; Inert atmosphere; A mixture of {1 -[4-(6-bromo-3-phenyl-imidazo[1 ,2-a]pyridin-2-yl)-phenyl]- cyclobutyl}-carbamic acid tert-butyl ester (50 mg) and 1 -tert-butoxycarbonyl-3- methylpyrazole-5-boronic acid (44 mg) in dioxane (1 mL) and water (0.43 mL) was placed under argon and [1 ,1 -bis-(diphenylphosphino)-ferrocene]- dichloropalladium-dichlormethane-complex (7.9 mg) added. The mixture was heated at 1 10 C under microwave irradiation for 60 minutes. On cooling the mixture was partitioned between DCM and water and extracted. The organic portion was dried and concentrated in vacuo to give the crude title compound which was used in the next step without further purification
  • 2
  • [ 381233-96-1 ]
  • [ 1217501-27-3 ]
  • 5-bromo-3-(3-methyl-1H-pyrazol-5-yl)pyridin-2-amine [ No CAS ]
  • 9-bromo-2-methylpyrazolo[1,5-c]pyrido[3,2-e]pyrimidin-5-ol [ No CAS ]
YieldReaction ConditionsOperation in experiment
With tetrakis(triphenylphosphine) palladium(0); caesium carbonate; In 1,2-dimethoxyethane; water; at 130 - 150℃; for 4.5h;Microwave irradiation; Pd(PPh3)4 (190.0 mg, 0.17 mmol) was added to suspension of 5-bromo-3-iodopyridin-2-amine (500.0 mg, 1.67 mmol), <strong>[1217501-27-3](1-(tert-butoxycarbonyl)-3-methyl-1H-pyrazol-5-yl)boronic acid</strong> (755.0 mg, 3.34 mmol), Cs2CO3 (1600.0 mg, 5.01 mmol), H2O (3.0 mL) and DME (12.0 mL). The reaction mixture was allowed to react in microwave under conditions of 100 W and 130 C. for 2 hours and 30 minutes, followed by 100 W and 150 C. for 2 hours and then cooled to room temperature. Water was added to the reaction mixture, and it was extracted 2 times with EtOAc. The organic layer was dried over anhydrous Na2SO4, filtered and then concentrated under reduced pressure. The residue was purified by column chromatography (MeOH:DCM=1:40) on silica. The fractions containing the product were collected and evaporated to obtain brown solid compound which is the mixture of 5-bromo-3-(3-methyl-1H-pyrazol-5-yl)pyridin-2-amine and 9-bromo-2-methylpyrazolo[1,5-c]pyrido[3,2-e]pyrimidin-5-ol (78.0 mg).
  • 3
  • [ 1217501-27-3 ]
  • tert-butyl (1-(9-bromo-2-methylpyrazolo[1,5-c]pyrido[3,2-e]pyrimidin-5-yl)azetidin-3-yl)(methyl)carbamate [ No CAS ]
  • 4
  • [ 1217501-27-3 ]
  • 1-(9-bromo-2-methylpyrazolo[1,5-c]pyrido[3,2-e]pyrimidin-5-yl)-N-methylazetidin-3-amine [ No CAS ]
  • 5
  • [ 1217501-27-3 ]
  • C10H6BrClN4 [ No CAS ]
  • 6
  • [ 1217501-27-3 ]
  • (6-bromo-[1,2,4]triazolo[1,5-a]pyridin-8-yl)methanol [ No CAS ]
  • (6-(3-methyl-1H-pyrazol-5-yl)-[1,2,4]triazolo[1,5-a]pyridin-8-yl)methanol [ No CAS ]
YieldReaction ConditionsOperation in experiment
73% With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; sodium carbonate; In 1,2-dimethoxyethane; at 100℃; a. Preparation of (6-(3-methyl-1H-pyrazol-5-yl)-[1,2,4]triazolo[1,5-a]pyridin-8-yl)methanol (14) Compound 5 (450 mg, 1.97 mmol, 1.0 eq), <strong>[1217501-27-3](2-tert-butoxycarbonyl-5-methyl-pyrazol-3-yl)boronic acid</strong> (937 mg, 4.14 mmol, 2.1 eq), Pd(dppf)Cl2.CH2Cl2 (144 mg, 0.197 mmol, 0.10 eq), 1 M sodium carbonate solution (1.97 mL, 1.97 mmol, 1 eq) and DME (10 mL) were added to a large microwave vial. The vial was capped and stirred overnight at 100 C. The reaction was washed with water and brine and extracted with EtOAc (2*). The organics were combined, dried (MgSO4), and concentrated to dryness. Purification by flash chromatography on silica gel afforded 330 mg (73%) of the title compound: 1H NMR (400 MHz, DMSO-d6) delta 9.15 (s, 1H), 8.45 (s, 1H), 8.16 (s, 1H), 6.63 (s, 1H), 5.62 (s, 1H), 4.88 (d, J=3.3 Hz, 2H), 2.28 (s, 3H); ES-MS [M+1]+: 230.2.
  • 7
  • [ 1217501-27-3 ]
  • 3-bromo-1-(6-methoxy-5-methylpyridin-3-yl)-4,5,7,8-tetrahydro-1H-oxepino[4,5-c]pyrazole [ No CAS ]
  • 1-(6-methoxy-5-methylpyridin-3-yl)-3-(3-methyl-1H-pyrazol-5-yl)-4,5,7,8-tetrahydro-1H-oxepino[4,5-c]pyrazole [ No CAS ]
YieldReaction ConditionsOperation in experiment
9 mg A mixture of 3-bromo-l-(6-methoxy-5-methylpyridin-3-yl)-4,5,7,8-tetrahydro-lH-oxepino[4,5- c]pyrazole (22 mg, 0.052 mmol) and (l-(te/-butoxycarbonyl)-3-methyl-lH-pyrazol-5-yl)boronic acid (25 mg, O.lllmmol) in 1,4-dioxane (0.5 mL) and water (0.215 mL) was treated with PdCl2(dtbpf) (3 mg, 4.60 muiotatauiotaomicronIota) and heated at 80 C using a microwave for 60 min. The reaction mixture was treated with a solution of (l-(tert-butoxycarbonyl)-3-methyl-lW-pyrazol-5-yl)boronic acid (25 mg, 0.111 mmol) in 1,4-dioxane (0.05 mL) and a solution of potassium phosphate (21 mg, 0.099 mmol) in in water (0.02 mL). The reaction mixture was heated at 80 C using a microwave for 120 min. Separately a mixture of 3-bromo-l-(6-methoxy-5-methylpyridin-3-yl)-4,5,7,8-tetrahydro-lW- oxepino[4,5-c]pyrazole (22 mg, 0.052 mmol) and (l-(iert-butoxycarbonyl)-3-methyl-lW-pyrazol-5- yl)boronic acid (25 mg, O.lllmmol) in 1,4-dioxane (0.550 mL) and water (0.215 mL) was treated with [l,3-bis(2,6-diisopropylphenyl)imidazole-2-ylidene)(3-chloropyridyl)dichloropalladium (3.5 mg, 5.20 muiotaetaomicronIota). The mixture was heated at 80 C using a microwave for 60 min. The reaction mixture was treated with a solution of potassium phosphate (21 mg, 0.099 mmol) in water (0.02 mL) and heated at 80 C using a microwave 120 min. Separately a mixture of 3-bromo-l-(6-methoxy-5-methylpyridin-3-yl)-4,5,7,8-tetrahydro-lW- oxepino[4,5-c]pyrazole (22 mg, 0.052 mmol) and (l-(tert-butoxycarbonyl)-3-methyl-lW-pyrazol-5- yl)boronic acid (25 mg, O.lllmmol) in 1,4-dioxane (0.5 mL) and water (0.215 mL) was treated with XPhos Pd G2 (4.09 mg, 5.20 Mmol). The mixture was heated at 80 C using a microwave 60 min. The reaction mixture was treated with a solution of (l-(tert-butoxycarbonyl)-3-methyl-lH-pyrazol-5- yl)boronic acid (25 mg, 0.111 mmol) dissolved in 1,4-dioxane (0.05 mL) and a solution of potassium phosphate (21 mg, 0.099 mmol) in water (0.02 mL) and heated at 80 C using a microwave for 120 min. The three reaction mixtures were combined and partitioned with DCM (10 mL) and water (10 mL). The organic layer was isolated and the aqueous layer was extracted with further DCM (3 x 10 mL). The combined organic layers were passed through a hydrophobic frit and concentrated under reduced pressure to give the crude product (123 mg). The crude product was purified using MDAP (Method A) to give the title compound (9 mg). LCMS (Method C): Rt = 0.96 min, MH+ 340.
  • 8
  • [ 1217501-27-3 ]
  • C14H12FIN4 [ No CAS ]
  • C18H17FN6 [ No CAS ]
YieldReaction ConditionsOperation in experiment
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate; In water; N,N-dimethyl-formamide; at 100℃; for 2h;Inert atmosphere; General procedure: Add N- (2,5-difluorobenzyl) -3-iodopyrazolo [1,5-a] pyrimidin-5-amine (0.52 mmol), 1-Boc-pyrazole-4-boronic acid pinacol Ester (0.78 mmol), anhydrous potassium carbonate (2.08 mmol), tetrakis (triphenylphosphine) palladium (0.052 mmol) were added to a 100 ml reaction tube, replaced with argon 3 times, and 10 ml of anhydrous DMF and 2 ml of water were added.The reaction was performed at 100 C for 2 h under an argon atmosphere, and monitored by TLC (petroleum ether: acetone = 2: 1).After the reaction was completed, it was cooled to 50 C, filtered through celite, and the filtrate was added with water and extracted with ethyl acetate.The organic phase was washed twice with saturated brine, dried over anhydrous sodium sulfate, and concentrated to obtain a crude oily black product. The crude product was purified by column chromatography (TLC, petroleum ether: acetone = 2: 1) to obtain a pale yellow solid.
  • 9
  • [ 1217501-27-3 ]
  • (R)-N-(1-(2,5-difluorophenyl)ethyl)-3-iodopyrazolo[1,5-a]pyrimidin-5-amine [ No CAS ]
  • C18H16F2N6 [ No CAS ]
YieldReaction ConditionsOperation in experiment
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate; In water; N,N-dimethyl-formamide; at 100℃; for 2h;Inert atmosphere; General procedure: Add N- (2,5-difluorobenzyl) -3-iodopyrazolo [1,5-a] pyrimidin-5-amine (0.52 mmol), 1-Boc-pyrazole-4-boronic acid pinacol Ester (0.78 mmol), anhydrous potassium carbonate (2.08 mmol), tetrakis (triphenylphosphine) palladium (0.052 mmol) were added to a 100 ml reaction tube, replaced with argon 3 times, and 10 ml of anhydrous DMF and 2 ml of water were added.The reaction was performed at 100 C for 2 h under an argon atmosphere, and monitored by TLC (petroleum ether: acetone = 2: 1).After the reaction was completed, it was cooled to 50 C, filtered through celite, and the filtrate was added with water and extracted with ethyl acetate.The organic phase was washed twice with saturated brine, dried over anhydrous sodium sulfate, and concentrated to obtain a crude oily black product. The crude product was purified by column chromatography (TLC, petroleum ether: acetone = 2: 1) to obtain a pale yellow solid.
  • 10
  • [ 1217501-27-3 ]
  • C14H11F2IN4 [ No CAS ]
  • C18H16F2N6 [ No CAS ]
YieldReaction ConditionsOperation in experiment
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate; In water; N,N-dimethyl-formamide; at 100℃; for 2h;Inert atmosphere; General procedure: Add N- (2,5-difluorobenzyl) -3-iodopyrazolo [1,5-a] pyrimidin-5-amine (0.52 mmol), 1-Boc-pyrazole-4-boronic acid pinacol Ester (0.78 mmol), anhydrous potassium carbonate (2.08 mmol), tetrakis (triphenylphosphine) palladium (0.052 mmol) were added to a 100 ml reaction tube, replaced with argon 3 times, and 10 ml of anhydrous DMF and 2 ml of water were added.The reaction was performed at 100 C for 2 h under an argon atmosphere, and monitored by TLC (petroleum ether: acetone = 2: 1).After the reaction was completed, it was cooled to 50 C, filtered through celite, and the filtrate was added with water and extracted with ethyl acetate.The organic phase was washed twice with saturated brine, dried over anhydrous sodium sulfate, and concentrated to obtain a crude oily black product. The crude product was purified by column chromatography (TLC, petroleum ether: acetone = 2: 1) to obtain a pale yellow solid.
 

Historical Records

Technical Information

Categories

Related Functional Groups of
[ 1217501-27-3 ]

Organoborons

Chemical Structure| 847818-68-2

A322975 [847818-68-2]

(1,3-Dimethyl-1H-pyrazol-5-yl)boronic acid

Similarity: 0.69

Chemical Structure| 1188405-87-9

A195288 [1188405-87-9]

(1-(tert-Butoxycarbonyl)-1H-pyrazol-4-yl)boronic acid

Similarity: 0.68

Chemical Structure| 847818-79-5

A131198 [847818-79-5]

1,3-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Similarity: 0.68

Chemical Structure| 947533-31-5

A438771 [947533-31-5]

(1-(tert-Butoxycarbonyl)-3,5-dimethyl-1H-pyrazol-4-yl)boronic acid

Similarity: 0.65

Chemical Structure| 552846-17-0

A109224 [552846-17-0]

tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate

Similarity: 0.63

Amides

Chemical Structure| 219580-32-2

A128668 [219580-32-2]

tert-Butyl 1H-pyrazole-1-carboxylate

Similarity: 0.69

Chemical Structure| 1188405-87-9

A195288 [1188405-87-9]

(1-(tert-Butoxycarbonyl)-1H-pyrazol-4-yl)boronic acid

Similarity: 0.68

Chemical Structure| 1018446-95-1

A243534 [1018446-95-1]

tert-Butyl 4-amino-1H-pyrazole-1-carboxylate

Similarity: 0.65

Chemical Structure| 947533-31-5

A438771 [947533-31-5]

(1-(tert-Butoxycarbonyl)-3,5-dimethyl-1H-pyrazol-4-yl)boronic acid

Similarity: 0.65

Chemical Structure| 552846-17-0

A109224 [552846-17-0]

tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate

Similarity: 0.63

Related Parent Nucleus of
[ 1217501-27-3 ]

Pyrazoles

Chemical Structure| 219580-32-2

A128668 [219580-32-2]

tert-Butyl 1H-pyrazole-1-carboxylate

Similarity: 0.69

Chemical Structure| 847818-68-2

A322975 [847818-68-2]

(1,3-Dimethyl-1H-pyrazol-5-yl)boronic acid

Similarity: 0.69

Chemical Structure| 1188405-87-9

A195288 [1188405-87-9]

(1-(tert-Butoxycarbonyl)-1H-pyrazol-4-yl)boronic acid

Similarity: 0.68

Chemical Structure| 847818-79-5

A131198 [847818-79-5]

1,3-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Similarity: 0.68

Chemical Structure| 1018446-95-1

A243534 [1018446-95-1]

tert-Butyl 4-amino-1H-pyrazole-1-carboxylate

Similarity: 0.65