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Chemical Structure| 1213205-62-9 Chemical Structure| 1213205-62-9

Structure of 1213205-62-9

Chemical Structure| 1213205-62-9

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Product Details of [ 1213205-62-9 ]

CAS No. :1213205-62-9
Formula : C9H12N2
M.W : 148.21
SMILES Code : N[C@H](C1CC1)C2=NC=CC=C2

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Application In Synthesis of [ 1213205-62-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1213205-62-9 ]

[ 1213205-62-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 885521-46-0 ]
  • [ 1213205-62-9 ]
  • [ 1430473-34-9 ]
YieldReaction ConditionsOperation in experiment
80% With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; General Method A iamide coupling) A DMF solution of 3-iodo-lH-indazole-5-carboxylic acid (1.0 equiv), DIPEA (3.0-5.0 equiv) and R 'NH (1.00-1.05 equiv) at 0 C or rt was treated with TBTU or BOP-C1 (1.05 equiv) added in one portion. The reaction was stirred allowing slowly to warm to rt. After several h or overnight stirring the crude reaction was subsequently diluted with H20. In the majority of examples a filtration and washing (H20) of the precipitate provided the desired material with the required purity or alternatively the material was purified directly by prep-HPLC or/and flash chromatography.
 

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