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Chemical Structure| 1208902-96-8 Chemical Structure| 1208902-96-8

Structure of 1208902-96-8

Chemical Structure| 1208902-96-8

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Product Details of [ 1208902-96-8 ]

CAS No. :1208902-96-8
Formula : C16H21N3O3
M.W : 303.36
SMILES Code : COC1C(OCCCN2CCOCC2)=CC2C(=NC=NC=2)C=1

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Application In Synthesis of [ 1208902-96-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1208902-96-8 ]

[ 1208902-96-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1208902-96-8 ]
  • [ 199327-61-2 ]
YieldReaction ConditionsOperation in experiment
85% With peracetic acid; sulfuric acid; In ethanol; at 60℃; for 12h; General procedure: To a solution of 6,7-dimethoxyquinazoline 1a (200.0 mg, 1.05 mmol) in ethanol (20 mL) were added 40percent peracetic acid (1.0mL, 5.26 mmol) and 0.01 mL sulfuric acid (1.8 mmol). After the reaction was stirred at 60°C for 4?12 h (see Table 2) and then cooled to room temperature, excess sodium bisulfite (541.8 mg, 5.26 mmol) was added to get rid of the peroxide. The solid was filtered off after stirring for 20 min, and the filtrate was concentrated under reduced pressure to give the crude product, which was washed by ethanol and petroleum ether to give 2a as a light yellow solid (179.7 mg, 83percent), mp>300°C.
 

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