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Chemical Structure| 1183825-71-9 Chemical Structure| 1183825-71-9

Structure of 1183825-71-9

Chemical Structure| 1183825-71-9

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Product Details of [ 1183825-71-9 ]

CAS No. :1183825-71-9
Formula : C10H14ClN
M.W : 183.68
SMILES Code : CC(C)C(C1=CC=CC=C1Cl)N
MDL No. :MFCD12780211

Safety of [ 1183825-71-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of [ 1183825-71-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1183825-71-9 ]

[ 1183825-71-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 885521-46-0 ]
  • [ 1183825-71-9 ]
  • [ 1430474-87-5 ]
YieldReaction ConditionsOperation in experiment
95% With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 25℃; for 12h; D. N-(l-(2-chlorophenyl)-2-methylpropyl)-3-iodo-lH-indazole-5-carboxamide The title compound was synthesized according to General Method A by using l-(2-chlorophenyl)-2- methylpropan-1 -amine (0.55 g, 2.99 mmol), DMF (11 mL), 3-iodo-lH-indazole-5-carboxylic acid (863 mg, 2.99 mmol), DIPEA (2.09 mL, 11.98 mmol) and TBTU (960 mg, 2.99 mmol). The resultant reaction mass stirred at 25C for 12 h and then quenched it in 0 (440 mL). The solid collected by filtration and was washed with H20 to provide the title compound (cream color solid, 1.29 g, 95%). NMR (400 MHz, DMSO-d6) delta 13.76 (s, 1H), 8.91 (d, .7=8.8 Hz, 1H), 7.91 (d, J=9.2 Hz, 1H), 7.74- 7.66 (m, 1H), 7.59 (d, J=8.8 Hz, 1H), 7.46-7.22 (m, 4H), 5.27 (t, J=9.2 Hz, 1H),2.20-2.15 (m, 1H), 1.08 (d, .7=6.0 Hz, 3H), 0.79 (d, J=6.8 Hz, 3H) ; MS ESI 454 [M + H]+, calcd for [Cl8H17CHN30 + H]+ 454.
 

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