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Chemical Structure| 116611-57-5 Chemical Structure| 116611-57-5

Structure of 116611-57-5

Chemical Structure| 116611-57-5

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Product Details of [ 116611-57-5 ]

CAS No. :116611-57-5
Formula : C10H21NO3
M.W : 203.28
SMILES Code : CCC[C@H](CO)NC(=O)OC(C)(C)C
MDL No. :MFCD22665918

Safety of [ 116611-57-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 116611-57-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 116611-57-5 ]

[ 116611-57-5 ] Synthesis Path-Downstream   1~2

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  • [ 116611-57-5 ]
  • [ 53308-95-5 ]
  • 2
  • [ 53308-95-5 ]
  • [ 116611-57-5 ]
YieldReaction ConditionsOperation in experiment
96% With borane; In tetrahydrofuran; methanol; Step 1. Preparation of Boc-Norvalinol: To a solution of Boc-norvaline (25.0 g, 0.115 mol) in tetrahydrofuran (461 mL), cooled to 0° C., was added borane/tetrahydrofuran complex (461 mL of a 1.0M solution in tetrahydrofuran) dropwise. After 1 h at 0° C., the solution was warmed to room temperature over a period of 1.5 h. TLC indicated that the reaction was complete. Methanol was added to quench the reaction. The solution was concentrated to yield the title compound (22.56 g, 96percent) as a foamy syrup. TLC of the products indicated satisfactory purity. Rf=0.34 (40percent ethyl acetate/hexanes).
 

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