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Chemical Structure| 1160923-98-7 Chemical Structure| 1160923-98-7

Structure of 1160923-98-7

Chemical Structure| 1160923-98-7

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Product Details of [ 1160923-98-7 ]

CAS No. :1160923-98-7
Formula : C6H2BrClN2
M.W : 217.45
SMILES Code : N#CC1=CN=CC(Br)=C1Cl
MDL No. :MFCD18261910
InChI Key :PRHCFBYVNSILBW-UHFFFAOYSA-N
Pubchem ID :68445829

Safety of [ 1160923-98-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of [ 1160923-98-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1160923-98-7 ]

[ 1160923-98-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 196205-06-8 ]
  • [ 1160923-98-7 ]
  • [ 1160923-99-8 ]
YieldReaction ConditionsOperation in experiment
62% A mixture of 5-bromo-4-chloronicotinonitrile (1.40 g, 6.43 mmol), <strong>[196205-06-8]5-amino-4-methylindole</strong> (0.94 g, 6.43 mmol) in 15 ml. of ethanol was heated at reflux overnight, then cooled to room temperature. The precipitate was filtered and washed with ethanol twice and diethyl ether once, then air-dried. The resultant HCI salt was suspended in methanol, treated with cone, aqueous ammonium hydroxide and concentrated in vacuo to dryness. The solid residue was washed with water and diethyl ether to give 1.3 g (62%) of 5-bromo-4-[(4-methyl-1 H-indol-5- yl)amino]nicotinonitrile as a pale gray solid; MS 327.1, 329.1 (M+H).
 

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[ 1160923-98-7 ]

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Related Parent Nucleus of
[ 1160923-98-7 ]

Pyridines

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