Home Cart Sign in  
Chemical Structure| 1154665-52-7 Chemical Structure| 1154665-52-7

Structure of 1154665-52-7

Chemical Structure| 1154665-52-7

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1154665-52-7 ]

CAS No. :1154665-52-7
Formula : C13H20FN3
M.W : 237.32
SMILES Code : CN(C)C1CCN(C2=CC=C(N)C=C2F)CC1
MDL No. :MFCD12439412

Safety of [ 1154665-52-7 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H312-H315-H318-H332-H335
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P330-P332+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 1154665-52-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1154665-52-7 ]

[ 1154665-52-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 1197953-49-3 ]
  • [ 1154665-52-7 ]
  • (2-((5-chloro-2-((4-(4-(dimethylamino)piperidin-1-yl)-3-fluorophenyl)amino)pyrimidine-4-yl)amino)phenyl)dimethylphosphine oxide [ No CAS ]
YieldReaction ConditionsOperation in experiment
36.1% With hydrogenchloride; In isopropyl alcohol; at 120℃;Inert atmosphere; Add compound 8a to a 25 mL single-mouth bottle with magnetic stirrer and condenser(760 mg, 3.21 mmol), compound 5a (1.01 g, 3.21 mmol)And ethylene glycol monomethyl ether (10mL), stir and dissolve, add hydrogen chloride isopropanol solution(4.82mmol, 0.96mL, 5M),The temperature was raised to 120 C under a nitrogen atmosphere and stirred to react overnight. Cool to room temperature,Add water (10 mL) and saturated sodium bicarbonate (5 mL) and dichloromethane (15 mL×3)The organic phase was combined, washed with saturated brine and dried over anhydrous sodium sulfate.Filtration, concentration, and residue over silica gel to give a white solid600 mg, the yield was 36.1%.
  • 2
  • [ 4876-59-9 ]
  • [ 1154665-52-7 ]
 

Historical Records