Home Cart Sign in  
Chemical Structure| 1142004-97-4 Chemical Structure| 1142004-97-4

Structure of 1142004-97-4

Chemical Structure| 1142004-97-4

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1142004-97-4 ]

CAS No. :1142004-97-4
Formula : C11H11N3O
M.W : 201.22
SMILES Code : NC1=NC=NC(C2=CC=CC=C2OC)=C1

Safety of [ 1142004-97-4 ]

Application In Synthesis of [ 1142004-97-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1142004-97-4 ]

[ 1142004-97-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1142004-97-4 ]
  • [ 22540-50-7 ]
  • [ 1142004-83-8 ]
YieldReaction ConditionsOperation in experiment
17% With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 0 - 120℃; for 4.75h; To a solution of 6-oxo-piperidine 3-carboxylic acid (0.21 g, 1.5 mmol) in dry DMF (10 ml) was added HBTU (1.13 g, 2.98 mmol), and DIPEA (0.30 g, 0.39 ml, 2.3 mmol) under ice cooled condition, then it was allowed to stir at room temperature for 45 min. To this reaction mixture was added the amine A (0.30 g, 1.5 mmol) in dry DMF dropwise under ice cooled condition. The reaction mixture was then heated for 4 h at 120 C. After the completion of reaction it was cooled, DMF was evaporated completely and then it was dissolved in ethyl acetate (30 ml), and was washed with water (2 x 15 ml), and then with brine, dried (Na2SO4), evaporated under reduced pressure. Final purification was done by column chromatography using flash silica gel (10% methanol/DCM) provided 78 mg (yield: 17%) of the desired product.
 

Historical Records