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Chemical Structure| 1119-19-3 Chemical Structure| 1119-19-3

Structure of 1119-19-3

Chemical Structure| 1119-19-3

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Product Details of [ 1119-19-3 ]

CAS No. :1119-19-3
Formula : C4H4O
M.W : 68.07
SMILES Code : CC#CC=O
MDL No. :MFCD12025190
InChI Key :REJPDMLLCDXIOV-UHFFFAOYSA-N
Pubchem ID :136875

Safety of [ 1119-19-3 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H225-H302-H312-H315-H318-H332-H335
Precautionary Statements:P210-P240-P241-P242-P243-P261-P264-P270-P271-P280-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P332+P313-P362-P370+P378-P403+P233-P403+P235-P405-P501
Class:3
UN#:1989
Packing Group:

Application In Synthesis of [ 1119-19-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1119-19-3 ]

[ 1119-19-3 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 1004-38-2 ]
  • [ 1119-19-3 ]
  • [ 20738-96-9 ]
  • [ 19191-82-3 ]
  • 2
  • [ 1004-38-2 ]
  • [ 1119-19-3 ]
  • [ 19191-82-3 ]
  • 3
  • [ 1119-19-3 ]
  • [ 108511-97-3 ]
  • C7H6N2O [ No CAS ]
  • 4
  • [ 1119-19-3 ]
  • [ 2605-68-7 ]
  • methyl (E)-2-methylhex-2-en-4-ynoate [ No CAS ]
YieldReaction ConditionsOperation in experiment
2.71 g at 50℃; for 1.75h; A solution of ylide 17 (15.0 g, 43.1 mmol, 1.00 eq) was added at rt to theblack suspension obtained in the oxidation. Then the mixture was heated to reflux (50 Coil bath) for 1 h 45 min and then filtered through a pad of celite (topped with a few mm ofsilica). The pad was rinsed thoroughly with ether, the combined filtrates wereconcentrated under reduced pressure and the residue was purified by columnchromatography (pent/Et2O 15:1→10:1→5:1) to afford ester 97 as a colourless liquid(2.71 g, 45%).TLC (hexane/EtOAc, 5:1): Rf = 0.521H-NMR (CDCl3, 400.1 MHz): δ = 6.60 (mc, 1H), 3.75 (s, 3H), 2.07 (mc, 3H), 2.03 (dd,J = 0.6 Hz, J = 1.2 Hz, 3H)13C-NMR (CDCl3, 100.6 MHz): δ = 167.8, 137.6, 120.5, 99.2, 76.6, 52.0, 15.1, 4.9.IR (neat, ν/cm-1) 2994, 2952, 2920, 2849, 2367, 2357, 2221, 1712 (s), 1618, 1435, 1386,1348, 1337, 1256 (s), 1191, 1175, 1118 (s), 1017, 974, 944, 891, 827, 802, 745 (s), 690,512, 481, 439, 425, 409.HRMS (EI): m/z calcd for C8H10O2 [M]+: 138.0676; found: 138.0676.
 

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