Home Cart Sign in  
Chemical Structure| 108723-79-1 Chemical Structure| 108723-79-1

Structure of 108723-79-1

Chemical Structure| 108723-79-1

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 108723-79-1 ]

CAS No. :108723-79-1
Formula : C6H15ClN2O
M.W : 166.65
SMILES Code : O=C(N(CC)CC)CN.[H]Cl
MDL No. :MFCD07366745

Safety of [ 108723-79-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of [ 108723-79-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 108723-79-1 ]

[ 108723-79-1 ] Synthesis Path-Downstream   1~13

  • 1
  • [ 108723-79-1 ]
  • [ 4521-61-3 ]
  • [ 363-20-2 ]
  • 2
  • [ 699-98-9 ]
  • [ 108723-79-1 ]
  • [ 500120-05-8 ]
  • 3
  • [ 1013-88-3 ]
  • [ 108723-79-1 ]
  • N2-(diphenylmethylene)-N1,N1-diethylglycinamide [ No CAS ]
  • 5
  • [ 946828-47-3 ]
  • [ 108723-79-1 ]
  • (S,S)-N,N-diethyl-bis[1-(quinolin-2-yl)ethyl]-aminoethanamide [ No CAS ]
  • 6
  • [ 108723-79-1 ]
  • N,N-diethyl-Nα-(diphenylmethylene)-D-phenylalaninamide [ No CAS ]
  • 7
  • [ 108723-79-1 ]
  • N,N-diethyl-Nα-(diphenylmethylene)-L-phenylalaninamide [ No CAS ]
  • 8
  • [ 500871-60-3 ]
  • [ 108723-79-1 ]
YieldReaction ConditionsOperation in experiment
88.5% With hydrogenchloride; at 20℃; for 16h; To a stirred solution of tert- butyl N-[(diethylcarbamoyl)methyl]carbamate (100 mg, 0.43 mmol) in l,4-dioxane (1 mL) was added HC1 (2 mL, 4M in l,4-dioxane) dropwise at room temperature. After stirring for 16 h at room temperature, the reaction mixture was filtered and the solid cake was washed with Et20 (3 x 10 mL) to obtain 2-amino-N,N-diethylacetamide hydrochloride (64 mg, 88.5%) as a white solid. ES-MS (m/z) [M+l]+ = 131.1.
  • 9
  • [ 108723-79-1 ]
  • [ 6959-47-3 ]
  • [ 831169-99-4 ]
  • 10
  • [ 1121-60-4 ]
  • [ 108723-79-1 ]
  • [ 831169-99-4 ]
  • 11
  • [ 10200-59-6 ]
  • [ 108723-79-1 ]
  • [ 1047619-84-0 ]
  • 12
  • [ 108723-79-1 ]
  • [ 73763-95-8 ]
  • [ 831170-00-4 ]
  • 13
  • 4-chloro-5-(2-methyl-6-(trifluoromethyl)pyridin-4-yl)-6-phenylpyrimidin-2-amine [ No CAS ]
  • [ 108723-79-1 ]
  • 2-((2-amino-5-(2-methyl-6-(trifluoromethyl)pyridin-4-yl)-6-phenylpyrimidin-4-yl)amino)-N,N-diethylacetamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
34.6% With triethylamine; In isopropyl alcohol; at 20 - 110℃; for 16h; To a stirred mixture of <strong>[108723-79-1]2-amino-N,N-diethylacetamide hydrochloride</strong> (64.0 mg, 0.38 mmol) and triethylamine (77.7 mg, 0.77 mmol) in i-PrOH (3 mL) was added 4-chloro-5-[2-methyl-6-(trifluoromethyl)pyridin-4-yl]-6-phenylpyrimidin-2-amine (140.1 mg, 0.38 mmol) at room temperature. After stirring for 16 h at 110 C, the reaction mixture was cooled and concentrated. The residue was purified by Prep-HPLC to afford 2-((2- amino-5-(2-methyl-6-(trifluoromethyl)pyridin-4-yl)-6-phenylpyrimidin-4-yl)amino)-N,N- diethylacetamide (61 mg, 34.6%) as an off-white solid. ES-MS (m/z) [M+l]+ = 459.1.
 

Historical Records

Technical Information

Categories