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Chemical Structure| 1083326-17-3 Chemical Structure| 1083326-17-3

Structure of 1083326-17-3

Chemical Structure| 1083326-17-3

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Product Details of [ 1083326-17-3 ]

CAS No. :1083326-17-3
Formula : C11H8BrClN2O2S
M.W : 347.62
SMILES Code : O=S(C1=CC=CC=C1)(NC2=CC(Br)=CN=C2Cl)=O
MDL No. :MFCD20482618

Safety of [ 1083326-17-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 1083326-17-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1083326-17-3 ]

[ 1083326-17-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1083326-17-3 ]
  • [ 1201645-46-6 ]
  • N-(5-(6-chloro-5-(phenylsulfonylamino)pyridin-3-yl)pyridin-3-yl)acetamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,4-dioxane; at 80.0℃; for 14.0h;Inert atmosphere; Add N-(5-bromo-2-chloropyridin-3-yl)benzenesulfonamide (200 mg) to a round bottom flask and add 1,4-dioxane (5 mL).<strong>[1201645-46-6]N-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)acetamide</strong> (165 mg), PdCl2 (dppf) 2 (47 mg) and potassium acetate (134 mg).The reaction system was heated to 80 C under argon for 14 hours. After the reaction,The solvent was evaporated to dryness under reduced pressure.Organic phase with water,After washing with saturated brine, it was dried over anhydrous sodium sulfate. The organic phase is filtered,The product was obtained by evaporation under reduced pressure.The crude product is purified by column chromatography on silica gel to give compound (54).
 

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