Home Cart Sign in  
Chemical Structure| 1076-67-1 Chemical Structure| 1076-67-1

Structure of 1076-67-1

Chemical Structure| 1076-67-1

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1076-67-1 ]

CAS No. :1076-67-1
Formula : C11H10S
M.W : 174.26
SMILES Code : SCC1=CC=C2C=CC=CC2=C1
MDL No. :MFCD00155255

Safety of [ 1076-67-1 ]

Application In Synthesis of [ 1076-67-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1076-67-1 ]

[ 1076-67-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1076-67-1 ]
  • [ 188869-05-8 ]
  • [ 188869-06-9 ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; In ice-water; acetonitrile; b) A solution of 2.78 g (10 mmol) of <strong>[188869-05-8]tert-butyl 3-bromo-4-oxo-piperidine-1-carboxylate</strong> and 2.09 g (12 mmol) of 2-mercaptomethylnaphthalene in 100 ml of absolute acetonitrile was treated with 13.8 g (100 mmol) of anhydrous potassium carbonate and thereafter the mixture was stirred at room temperature for 18 hours. The reaction mixture was filtered, the filtrate was poured on to ice-water and adjusted to pH 2-3 with concentrated hydrochloric acid; the aqueous phase was extracted three times with 200 ml of ethyl acetate each time, the organic phase was washed once with 200 ml of water, dried over magnesium sulphate, filtered and concentrated in a water-jet vacuum. The crude product (5.5 g) was chromatographed on silica gel with hexane and ethyl acetate as the eluent. The product was recrystallized from ethyl acetate and hexane. There were obtained 2.27 g (61percent of theory) of tert-butyl (3RS)-3-(naphthalen-2-ylmethylthio)-4-oxo-piperidine-1-carboxylate as a colourless solid; MS: 371 (M)+.
 

Historical Records