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Chemical Structure| 1076-59-1 Chemical Structure| 1076-59-1

Structure of 1076-59-1

Chemical Structure| 1076-59-1

3-Phenylisoxazol-5(4H)-one

CAS No.: 1076-59-1

4.5 *For Research Use Only !

Cat. No.: A600396 Purity: 97%

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Product Details of [ 1076-59-1 ]

CAS No. :1076-59-1
Formula : C9H7NO2
M.W : 161.16
SMILES Code : O=C1CC(C2=CC=CC=C2)=NO1
MDL No. :MFCD00003158
InChI Key :IHKNLPPRTQQACK-UHFFFAOYSA-N
Pubchem ID :70641

Safety of [ 1076-59-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340+P312-P305+P351+P338-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 1076-59-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1076-59-1 ]

[ 1076-59-1 ] Synthesis Path-Downstream   1~5

  • 1
  • [ 2346-00-1 ]
  • [ 1199-01-5 ]
  • [ 1076-59-1 ]
  • [ 40052-00-4 ]
  • 2
  • [ 2346-00-1 ]
  • [ 1076-59-1 ]
  • [ 40051-98-7 ]
  • 4
  • [ 463-49-0 ]
  • [ 156150-67-3 ]
  • [ 1076-59-1 ]
  • 4,4-bis[2-(3-chloro-4-fluorophenyl)prop-2-en-1-yl]-3-phenylisoxazol-5(4H)-one [ No CAS ]
  • 5
  • [ 6642-31-5 ]
  • [ 391-12-8 ]
  • [ 1076-59-1 ]
  • 1',3'-dimethyl-3-phenyl-8-(trifluoromethyl)-9H-spiro[isoxazolo[5,4-b]quinoline-4,5'-pyrrolo[2,3-d]pyrimidine]-2',4',6'(1'H,3'H,7'H)-trione [ No CAS ]
YieldReaction ConditionsOperation in experiment
91% With Amberlyst-15; In methanol; at 80℃; for 5h; General procedure: In a 25 mL round bottom flask, isatins 1 (1 mmol), 3-phenylisoxazol-5(4H)-one 2 (1 mmol) or 3-ethylisoxazol-5(4H)-one 7 (1 mmol), pyrazol-5-amine 3 (1 mmol) or 6-aminopyrimidine-2,4-(1H,3H)-dione 5 (1 mmol), and Amberlyst-15 (100 mg) were stirred in CH3OH (5.0 mL) at 80 C. When the reaction was completed (detected by TLC), the spherical catalyst was separated by a sieve at once under hot condition. Then, the reaction mixture was cooled to room temperature, and solid precipitation occurred. After filtration, the crude product was recrystallized from EtOH and DMF to give pure compound.
 

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