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Chemical Structure| 106129-86-6 Chemical Structure| 106129-86-6

Structure of 106129-86-6

Chemical Structure| 106129-86-6

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Product Details of [ 106129-86-6 ]

CAS No. :106129-86-6
Formula : C11H13NO2
M.W : 191.23
SMILES Code : O=C(C1=CC=CC=C1O)/C=C/N(C)C
MDL No. :MFCD00172108
InChI Key :SVBCOAAIOJDZNC-BQYQJAHWSA-N
Pubchem ID :5715945

Safety of [ 106129-86-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

Application In Synthesis of [ 106129-86-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 106129-86-6 ]

[ 106129-86-6 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 106129-86-6 ]
  • [ 61348-47-8 ]
YieldReaction ConditionsOperation in experiment
5.22 g With hydroxylamine hydrochloride; In ethanol; at 78℃; for 1h; To a 100 mL flask was added 15 mL N-methylpyrrolidone, 1-(2-hydroxyphenyl) ethanone (5.03 g, 36.87mmol) and dimethoxy-N,N-dimethylmethanamine (6.21 g, 52.15 mmol) at room temperature. Thereaction mixture was heated to 90 C, stirred at 90 C for 40 min, then cooled to room temperature.Ethanol (50 mL) and hydroxylamine hydrochloride (3.84 g, 55.19 mmol) were added, then the solutionwas heated to 78 C and stirred for 1 h. The reaction mixture was concentrated. The residue washeated to 45 C, then, 125 mL water was added dropwise over 0.5 h. The solution was stirred at 45 Cfor 30 min, then cooled to room temperature and stirred overnight before the solid was collected byfiltration, washed with 20 mL water and dried in an evaporator at 50 C for 4 h to afford 2-(isoxazol-5-yl)phenol as a white solid 5.22 g, (87.7%).
  • 3
  • [ 106129-86-6 ]
  • [ 98-80-6 ]
  • [ 574-12-9 ]
 

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