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Chemical Structure| 10489-75-5 Chemical Structure| 10489-75-5

Structure of 10489-75-5

Chemical Structure| 10489-75-5

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Product Details of [ 10489-75-5 ]

CAS No. :10489-75-5
Formula : C6H4O3S2
M.W : 188.22
SMILES Code : O=C1C2=C(SCCS2)C(O1)=O
MDL No. :MFCD00223990
InChI Key :MXSSHXZXAAXCOW-UHFFFAOYSA-N
Pubchem ID :82669

Safety of [ 10489-75-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 10489-75-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 10489-75-5 ]

[ 10489-75-5 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 138-30-7 ]
  • [ 10489-75-5 ]
  • [ 24519-76-4 ]
  • 2
  • [ 15992-83-3 ]
  • [ 10489-75-5 ]
  • 5-hydroxy-6-(1,8-naphthyridin-2-yl)-7-oxo-2,3,6,7-tetrahydro-1,4-dithiino[2,3-c]pyrrole [ No CAS ]
YieldReaction ConditionsOperation in experiment
In diphenylether; acetic acid; Preparation of 5,7-dioxo-6-(1,8-naphthyridin-2-yl)-2,3,6,7-tetrahydro-1,4-dithiino[2,3-c]pyrrole (16.0 g.), m.p. 200 C., by reacting <strong>[15992-83-3]2-amino-1,8-naphthyridine</strong> (8.65 g.) with 5,6-dihydro-1,4-dithiine-2,3-dicarboxylic acid anhydride (22.0 g.) [prepared according to the method of H. R. Schweizer, Helv. Chim. Acta, 52, 2229 (1969)] in diphenyl ether (70 cc.) at 150 C. for half an hour, in the presence of anhydrous acetic acid (0.4 cc.). Preparation of 5-hydroxy-6-(1,8-naphthyridin-2-yl)-7-oxo-2,3,6,7-tetrahydro-1,4-dithiino[2,3-c]pyrrole (13.0 g.), m.p. 260 C., by reacting sodium borohydride (2.15 g.) with 5,7-dioxo-6-(1,8-naphthyridin-2-yl)-2,3,6,7-tetrahydro-1,4-dithiino[2,3-c]pyrrole (18.0 g.) in anhydrous tetrahydrofuran (200 cc.) to which anhydrous methanol (80 cc.) has been added gradually, at a temperature not exceeding 40 C.
 

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