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Chemical Structure| 104777-74-4 Chemical Structure| 104777-74-4

Structure of 104777-74-4

Chemical Structure| 104777-74-4

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Product Details of [ 104777-74-4 ]

CAS No. :104777-74-4
Formula : C7H13NO
M.W : 127.18
SMILES Code : O=C1C(CC)CNCC1
MDL No. :MFCD13191638

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Application In Synthesis of [ 104777-74-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 104777-74-4 ]

[ 104777-74-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 104777-74-4 ]
  • [ 24424-99-5 ]
  • [ 117565-57-8 ]
YieldReaction ConditionsOperation in experiment
83% Compound 26 (2.90 g, 10.2 mmol) was suspended in 6 N HCl (85 ml) and refluxed for 16 h. The product was concentrated and azeotroped three times with isopropanol to give a yellow solid. The solid was dissolved in 1:1 CH2Cl2:MeOH (50 ml) and Et3N (3.08 g, 4.3 ml, 30.5 mmol) and di-t-butyl dicarbonate (3.32 g, 15.2 mmol) were added. The mixture was stirred at 23 C. for 16 h, then concentrated. 0.5 N NaOH (50 ml) was added and the mixture extracted with CH2Cl2. The combined organic extracts were dried (MgSO4), filtered, and concentrated. Purification by silica gel chromatography (eluant: 10% EtOAc-hexane) gave 1.92 g (8.46 mmol, 83%) of the product 27A as a colorless oil. MS (ES for M+1): m/e 228
 

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