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Chemical Structure| 1036712-58-9 Chemical Structure| 1036712-58-9

Structure of 1036712-58-9

Chemical Structure| 1036712-58-9

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Product Details of [ 1036712-58-9 ]

CAS No. :1036712-58-9
Formula : C17H14BrNO2
M.W : 344.20
SMILES Code : O=C1N(CC2=CC=C(OC)C=C2)C=CC3=C1C=CC(Br)=C3
MDL No. :MFCD26396107

Safety of [ 1036712-58-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 1036712-58-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1036712-58-9 ]

[ 1036712-58-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 876189-18-3 ]
  • [ 1036712-58-9 ]
  • [ 1070292-87-3 ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; In N,N-dimethyl-formamide; at 95.0℃; for 17.0h; A mixture of 6-bromo-2-(4-methoxy-benzyl)-2H-isoquinolin-1-one (product of step iv) ) (1.2 g), intermediate 2 (0.7g), potassium carbonate (1.0 g) and tetrakis(triphenylphosphine)palladium(0) (0.4 g) in lambda/,lambda/-dimethylformamide (2OmL) was heated to 950C for 17 hours. The reaction mixture was diluted with ethyl acetate and washed with water and brine. The organic phase was dried, filtered and evaporated. The residue was purified (SiO2, 1 :2 ethyl acetate:iso-hexane as eluent) to yield the sub-titled compound (1.03g).MS: APCI(+ve) 414 [M+H]+
 

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