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Chemical Structure| 1027717-63-0 Chemical Structure| 1027717-63-0

Structure of 1027717-63-0

Chemical Structure| 1027717-63-0

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Product Details of [ 1027717-63-0 ]

CAS No. :1027717-63-0
Formula : C11H5F6N
M.W : 265.15
SMILES Code : N#C/C=C/C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1
MDL No. :N/A

Safety of [ 1027717-63-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P260-P280-P301+P312+P330-P305+P351+P338+P310

Application In Synthesis of [ 1027717-63-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1027717-63-0 ]

[ 1027717-63-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 328-72-3 ]
  • [ 32673-25-9 ]
  • [ 19293-63-1 ]
  • [ 107-13-1 ]
  • [ 1027717-63-0 ]
YieldReaction ConditionsOperation in experiment
69% With NBu4Br;palladium diacetate; In ISOPROPYLAMIDE; water; Example 16 Synthesis of 3,5-bis(trifluoromethyl)cinnamonitrile 0.382 g (7.2 mmol) of acrylonitrile, 38.7 mg (120 mumol) of NBu4Br, 6.7 mg (30 mumol) of palladium acetate and 26.7 mg (120 mumol) of phenyldi(t-butyl)phosphine are weighed into a Schlenk vessel. 1.49 g (6 mmol) of <strong>[328-72-3]3,5-bis(trifluoromethyl)chlorobenzene</strong> and 1.53 ml (7.2 mmol) of dicyclohexylmethylamine and also 3.5 ml of dimethylacetamide are then added. The Schlenk vessel is placed in a heating bath at 130 C. and the contents are stirred. After 4 hours, the contents are poured into 30 ml of water and the product is extracted by shaking with t-butyl methyl ether. After drying the organic phase over MgSO4, the solvent is removed under reduced pressure and the product is isolated. Orange oil, yield: 69%.
 

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