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Chemical Structure| 1020722-10-4 Chemical Structure| 1020722-10-4

Structure of 1020722-10-4

Chemical Structure| 1020722-10-4

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Product Details of [ 1020722-10-4 ]

CAS No. :1020722-10-4
Formula : C11H7BrN2O
M.W : 263.09
SMILES Code : N#CCC(C1=CNC2=C1C=C(Br)C=C2)=O
MDL No. :MFCD09839790

Safety of [ 1020722-10-4 ]

Application In Synthesis of [ 1020722-10-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1020722-10-4 ]

[ 1020722-10-4 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 1020722-10-4 ]
  • [ 873-95-0 ]
  • [ 874-42-0 ]
  • [ 1315505-88-4 ]
YieldReaction ConditionsOperation in experiment
89% With ammonium acetate; In butan-1-ol; at 120℃; for 8h; General procedure: Aldehyde 1 (0.5 mmol), 3-cynaoacetyl indole 2 (0.5 mmol), and 3-amino-2-enone 3 (0.5 mmol) at 120 C was stirred for 8 h or 12 h in 2 mL n-BuOH in the presence of NH4OAc (0.5 mmol). After the completion (monitored by TLC), water (50 mL) was added. The mixture was filtered and the solid product was washed with water (3×5 mL). The crude product was purified by recrystallization from EtOH to give 4.
  • 2
  • [ 1020722-10-4 ]
  • [ 873-95-0 ]
  • [ 1122-91-4 ]
  • [ 1315505-77-1 ]
YieldReaction ConditionsOperation in experiment
88% With ammonium acetate; In butan-1-ol; at 120℃; for 8h; General procedure: Aldehyde 1 (0.5 mmol), 3-cynaoacetyl indole 2 (0.5 mmol), and 3-amino-2-enone 3 (0.5 mmol) at 120 C was stirred for 8 h or 12 h in 2 mL n-BuOH in the presence of NH4OAc (0.5 mmol). After the completion (monitored by TLC), water (50 mL) was added. The mixture was filtered and the solid product was washed with water (3×5 mL). The crude product was purified by recrystallization from EtOH to give 4.
  • 3
  • [ 1020722-10-4 ]
  • [ 60481-51-8 ]
  • C19H17BrN4 [ No CAS ]
 

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Technical Information

• Alkyl Halide Occurrence • Baeyer-Villiger Oxidation • Barbier Coupling Reaction • Baylis-Hillman Reaction • Blaise Reaction • Bucherer-Bergs Reaction • Catalytic Hydrogenation • Clemmensen Reduction • Complex Metal Hydride Reductions • Corey-Bakshi-Shibata (CBS) Reduction • Corey-Chaykovsky Reaction • Fischer Indole Synthesis • General Reactivity • Grignard Reaction • Henry Nitroaldol Reaction • Hiyama Cross-Coupling Reaction • Horner-Wadsworth-Emmons Reaction • Hydride Reductions • Kinetics of Alkyl Halides • Kumada Cross-Coupling Reaction • Lawesson's Reagent • Leuckart-Wallach Reaction • McMurry Coupling • Meerwein-Ponndorf-Verley Reduction • Passerini Reaction • Paternò-Büchi Reaction • Petasis Reaction • Peterson Olefination • Pictet-Spengler Tetrahydroisoquinoline Synthesis • Preparation of Aldehydes and Ketones • Preparation of Amines • Prins Reaction • Reactions of Aldehydes and Ketones • Reactions of Alkyl Halides with Reducing Metals • Reactions of Amines • Reactions of Dihalides • Reformatsky Reaction • Ritter Reaction • Robinson Annulation • Schlosser Modification of the Wittig Reaction • Schmidt Reaction • Specialized Acylation Reagents-Ketenes • Stille Coupling • Stobbe Condensation • Substitution and Elimination Reactions of Alkyl Halides • Suzuki Coupling • Tebbe Olefination • Thorpe-Ziegler Reaction • Ugi Reaction • Wittig Reaction • Wolff-Kishner Reduction

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