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Type HazMat fee for 500 gram (Estimated)
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Chemical Structure| 10124-78-4 Chemical Structure| 10124-78-4

Structure of 10124-78-4

Chemical Structure| 10124-78-4

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Product Details of [ 10124-78-4 ]

CAS No. :10124-78-4
Formula : C11H7N
M.W : 153.18
SMILES Code : [C-]#[N+]C1=CC=C2C=CC=CC2=C1
MDL No. :MFCD06200692
InChI Key :ZZKQDMRCHFQQCQ-UHFFFAOYSA-N
Pubchem ID :16217475

Safety of [ 10124-78-4 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H315-H319-H331-H335
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P330-P332+P313-P337+P313-P361-P403+P233-P405-P501
Class:6.1
UN#:2811
Packing Group:

Application In Synthesis of [ 10124-78-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 10124-78-4 ]

[ 10124-78-4 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 109-01-3 ]
  • [ 10124-78-4 ]
  • [ 10165-86-3 ]
  • [ 947756-66-3 ]
YieldReaction ConditionsOperation in experiment
With acetic acid; In trifluoroethanol; for 2h; Step A: Methyl-6-[1-(4-methylpiperazin-1-yl)-2-(2-naphthylamino)-2-oxoethyl]nicotinate. Methyl 6-formylnicotinate (50.0 mg, 0.303 mmol), acetic acid (19.0 muL, 0.333 mmol), N-methylpiperizine (40.4 muL, 0.364 mmol), and 2-napthylisocyanide (51.0 mg, 0.333 mmol) were dissolved in 100 muL of TFE. The solution was allowed to stir for 2 h then purified by reverse phase HPLC to give the desired product MS cal'd 419 (MH+), exp 419 (MH+).
  • 2
  • [ 7504-94-1 ]
  • [ 3268-49-3 ]
  • [ 10124-78-4 ]
  • [ 1610342-61-4 ]
  • 3
  • [ 53137-27-2 ]
  • [ 10124-78-4 ]
  • [ 100-52-7 ]
  • [ 106-49-0 ]
  • 2,4-dimethyl-N-(2-(naphthalen-1-ylamino)-2-oxo-1-phenylethyl)-N-(p-tolyl)thiazole-5-carboxamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
18% General procedure: The aldehyde (0.8 equivalent) and amine (0.7 equivalent) were dissolved in methanol (2.0 mL) and stirred for two to 3 h depending upon the starting material. The acid (100 mg, 1 equivalent) and isocyanide (0.7 equivalent) were added in the reaction mixture and further stirred. The reaction mixture was monitored using TLC analysis.Water (4 mL) was added upon completion of the reaction.The resulted solid was filtered off and dissolved in ethyl acetate(10 mL), washed with water (2 3 mL) and dried over sodium sulphate. The crude product was purified using silica gel column chromatography. The ethyl acetate:hexane (6:4) solvent system was used for the purification of these compounds.
 

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