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Chemical Structure| 10004-17-8 Chemical Structure| 10004-17-8

Structure of 10004-17-8

Chemical Structure| 10004-17-8

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Product Details of [ 10004-17-8 ]

CAS No. :10004-17-8
Formula : C5H10O3
M.W : 118.13
SMILES Code : OCC1(C)OCCO1
MDL No. :MFCD22071617

Safety of [ 10004-17-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335-H227
Precautionary Statements:P210-P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P370+P378-P403+P233-P403+P235-P405-P501

Application In Synthesis of [ 10004-17-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 10004-17-8 ]

[ 10004-17-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 10004-17-8 ]
  • [ 67515-59-7 ]
  • [ 871795-91-4 ]
YieldReaction ConditionsOperation in experiment
With potassium tert-butylate; In tetrahydrofuran; at 0℃; for 0.5h; Example 1: 4-f2-cvano-2-(4-trif)uoromethoxvbenzoyiamino)-1 -propoxy]-3- trifluoromethylbenzamide a) In 30 ml of tetrahydrofuran 1.13 g of <strong>[67515-59-7]4-fluoro-3-trifluoromethylbenzonitrile</strong> and 1.87 g of (2-methyl-2-hydoxymethyl-[1,3]dioxolan are diluted and cooled to 0C. Then a cold solution of 0.73 g potassium t-butoxide in tetrahydrofuran is added dropwise. After stirring for 30 min at 0C the reaction mixture is diluted with 50 ml of ethyl acetate and washed twice with a saturated solution of ammonium chloride, water and brine. The organic phase is finally dried over magnesium sulfate, filtered and concentrated under vacuum. The residue is then stirred with hexane, filtered and dried to yield amorphous crystals of 4-(2-methyl-[1,3]dioxolan-2- ylmethoxy] )-3-trifluoromethylbenzonitrile.
 

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