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Chemical Structure| 34386-72-6 Chemical Structure| 34386-72-6

Structure of 34386-72-6

Chemical Structure| 34386-72-6

1-(2-Aminoethyl)pyrimidine-2,4(1H,3H)-dione

CAS No.: 34386-72-6

4.5 *For Research Use Only !

Cat. No.: A566459 Purity: 97%

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Product Details of [ 34386-72-6 ]

CAS No. :34386-72-6
Formula : C6H9N3O2
M.W : 155.16
SMILES Code : O=C1NC(C=CN1CCN)=O
MDL No. :MFCD16683348
InChI Key :JPNNMAWXXJIGMU-UHFFFAOYSA-N
Pubchem ID :10964739

Safety of [ 34386-72-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Application In Synthesis of [ 34386-72-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 34386-72-6 ]

[ 34386-72-6 ] Synthesis Path-Downstream   1~7

  • 6
  • [ 34386-72-6 ]
  • [ 473257-46-4 ]
  • 5-chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(methylsulfonyl)-1H-indole-2-carboxamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
35% With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20℃; for 12.0h; General procedure: Intermedite 16 (0.69mmol, 1 equiv.), 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC) (0.26g, 1.38mmol, 2 equiv.), 4-dimethylaminopyridineand (DMAP) (0.17g, 1.38mmol, 2 equiv.) and different appropriate sulfanilamides (1.5 equiv.) were dissolved in DMF (10mL). The reaction mixture was stirred at ambient temperature for 12h and then evaporated under reduced pressure. Water (30mL) was added and extracted with EA (3×10mL). Combined organic phase was washed with brine, dried over anhydrous MgSO4, filtered and concentrated. The residue was purified on silica gel using EA-PE system and pure fractions were collected, concentrated and recrystallized, giving the desired compounds (41-48).
  • 7
  • C12H16N3O5Pol [ No CAS ]
  • [ 34386-72-6 ]
  • C18H23N6O6Pol [ No CAS ]
 

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Categories

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