STAT3: A Critical Target in Cancer Research
In the frontier of cancer research, STAT3 emerges as a crucial signalling molecule expressed across various tissues, regulating genes associated with cancer cell growth, proliferation, angiogenesis, metastasis, drug resistance, and immune evasion. Its persistent activation is implicated in multiple oncogenic mechanisms, establishing it as a primary target in cancer research.
2025-05-29
Advances in the Synthesis of Cyclopropylamine
Professor Philippe Bertus , currently affiliated with the Centre National de la Recherche Scientifique (CNRS) and Le Mans Université , spent years specializing in organic and polymer chemistry. His research portfolio comprises over 110 scientific publications encompassing organic synthesis and catalytic reactions. In collaboration with Julien Caillé, they contributed a comprehensive review titled "Advances in the Synthesis of Cyclopropylamines" that outlines recent methodological breakthroughs in the field.
2025-05-16
From Mechanism to Medicine: Recent Advances in Ferroptosis from Top-Tier Publications
Ferroptosis is a distinct form of programmed cell death characterized by iron-dependent lipid peroxidation, first formally described by Dr.Brent Stockwell in 2012. Unlike apoptosis, necrosis, and autophagy, ferroptosis is driven by intracellular iron accumulation and lipid peroxides.
2025-04-30
Sulfilimines: An Underexplored Bioisostere for Drug Design?
In the ever-evolving landscape of medicinal chemistry, searching for novel functional groups with optimized pharmacological properties remains a key driver of innovation. While sulfoximines have gained increasing traction as aza-analogs of sulfones in both FDA-approved drugs and agrochemicals, a newer class—sulfilimines—is now emerging as a promising, underutilized scaffold for drug design. Pioneering studies by Ellman, Gnamm, and most recently by Arvidsson and Ritter’s groups have demonstrated the chemical versatility, metabolic stability, and synthetic utility of sulfilimines in the development of bioactive molecules.
2025-04-21
World Cancer Day 2025: Breakthroughs and Trends in Anti-Cancer Drug Development
On World Cancer Day 2025, we reflect on the progress in cancer research, especially small-molecule drugs and precision medicine. Advances in AI and targeted therapies are transforming cancer care, and AmBeed proudly supports researchers driving these breakthroughs. Together, we move closer to a cancer-free future.
2025-02-04
Harnessing Photocatalytic Single-Electron Oxidation: Radical Precursors for Efficient Metallaphotoredox Couping Reactions
Elevate your photoredox catalysis with our premium radical precursors, meticulously crafted for efficient radical generation via single-electron oxidation! Explore our diverse product lineup, including carboxylic acids, alkylboron derivatives, 1,4-dihydropyridines, and more—ideal for metallaphotoredox systems and coupling reactions.
2025-01-17
Innovation in Action: R&D Center
Welcome to learn more about our state-of-the-art R&D Center, where our commitment to innovation drives our success. The strength of our R&D capabilities lies in our expansive 10,000 m² facility, advanced laboratories, and a team of over 200 experienced scientists. This robust foundation enables us to push the boundaries of science and technology, develop groundbreaking compounds, and consistently create superior products that lead the industry.
2024-09-25
World Mental Health Day 2024: Prioritizing Mental Health in the Workplace for a Healthier Future
On World Mental Health Day 2024, let's prioritize mental well-being in the workplace. With the theme "It is Time to Prioritize Mental Health in the Workplace," we aim to create inclusive environments where everyone can thrive. Take a moment to care for your mind and support your colleagues—together, we can build healthier, more productive workspaces.
2024-10-10