Triazole Derivatives

Triazole antifungal agents are extensively utilized for both the prevention and treatment of fungal infections. They work by inhibiting lanosterol 14α-demethylase, which subsequently disrupts the synthesis of ergosterol, a vital component of the fungal cell membrane, thereby halting fungal growth. Due to this inhibitory mechanism, these drugs generally exhibit fungistatic properties. The affinity for this enzyme varies among different triazoles, influencing their potency and spectrum of activity. Most triazoles are considered fungistatic, except for voriconazole, which can act as a fungicide against Aspergillus species. The triazole antifungal drugs include fluconazole, isavuconazole, itraconazole, voriconazole, pramiconazole, ravuconazole, and posaconazole.

Triazole Derivatives

1H-1,2,4-Triazole-1-carboximidamide hydrochloride
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A42189919503-26-597%

1H-1,2,4-Triazole-1-carboximidamide hydrochloride

$5.0/5g Detail

Ethyl 5-methyl-1H-1,2,4-triazole-3-carboxylate
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A37452840253-47-297%

Ethyl 5-methyl-1H-1,2,4-triazole-3-carboxylate

$357.0/10g Detail

1-Methyl-1H-1,2,4-triazole-3-carbaldehyde
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A462359126748-87-695%

1-Methyl-1H-1,2,4-triazole-3-carbaldehyde

$61.0/100mg Detail

3-(1H-1,2,4-Triazol-1-yl)propanoic acid
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A22464276686-84-597%

3-(1H-1,2,4-Triazol-1-yl)propanoic acid

$351.0/5g Detail

2-(3,5-Dimethyl-1H-1,2,4-triazol-1-yl)acetic acid
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A158055684249-99-895%

2-(3,5-Dimethyl-1H-1,2,4-triazol-1-yl)acetic acid

$20.0/250mg Detail

5,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylic acid
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A11497787253-62-197%

5,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylic acid

$21.0/250mg Detail

(2R,3R)-2-(2,5-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol
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A679447241479-72-195%

(2R,3R)-2-(2,5-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol

$391.0/25g Detail

2-(3-Methyl-1H-1,2,4-triazol-5-yl)pyridine
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A19780825433-36-797%

2-(3-Methyl-1H-1,2,4-triazol-5-yl)pyridine

$25.0/1g Detail

(1-Ethyl-1H-1,2,4-triazol-5-yl)methanol
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A453769215868-81-895%

(1-Ethyl-1H-1,2,4-triazol-5-yl)methanol

$198.0/5g Detail

Ethyl 3-benzyl-1H-1,2,4-triazole-5-carboxylate
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A207119648430-85-797%

Ethyl 3-benzyl-1H-1,2,4-triazole-5-carboxylate

$29.0/100mg Detail

5-(4-Methoxyphenyl)-4H-1,2,4-triazol-3-amine
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A54864054464-14-195%

5-(4-Methoxyphenyl)-4H-1,2,4-triazol-3-amine

$123.0/1g Detail

7-Chloro-5-methyl-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine
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A558222885461-50-798%

7-Chloro-5-methyl-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine

$321.0/1g Detail

3-(Pyridin-3-yl)-1H-1,2,4-triazol-5-amine
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A71759635607-27-395%

3-(Pyridin-3-yl)-1H-1,2,4-triazol-5-amine

$198.0/1g Detail

5-Amino-4H-1,2,4-triazole-3-carboxylic acid
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A1129723641-13-295%

5-Amino-4H-1,2,4-triazole-3-carboxylic acid

$139.0/1kg Detail

3-Bromo-1H-1,2,4-triazole
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A35672315182-40-898%

3-Bromo-1H-1,2,4-triazole

$660.0/500g Detail

5-Bromo-1-methyl-1H-1,2,4-triazole
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A11442916681-72-498%

5-Bromo-1-methyl-1H-1,2,4-triazole

$6.0/250mg Detail

2-(1H-1,2,4-Triazol-3-yl)pyridine
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A27621923195-62-297%

2-(1H-1,2,4-Triazol-3-yl)pyridine

$7.0/250mg Detail

(1H-1,2,4-Triazol-1-yl)methanol
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A14511874205-82-695%

(1H-1,2,4-Triazol-1-yl)methanol

$17.0/1g Detail

4-(4H-1,2,4-Triazol-4-yl)benzoic acid
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A891756157069-48-298%

4-(4H-1,2,4-Triazol-4-yl)benzoic acid

$158.0/5g Detail

5-Phenyl-1H-1,2,4-triazol-3-amine
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A2366204922-98-997%

5-Phenyl-1H-1,2,4-triazol-3-amine

$298.0/5g Detail

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