Products Cited in Publications Worldwide 2-Metoksypropan-1-ol. Metoda oznaczania w powietrzu na stanowiskach pracy z zastosowaniem chromatografii gazowej

2-Metoksypropan-1-ol. Metoda oznaczania w powietrzu na stanowiskach pracy z zastosowaniem chromatografii gazowej

Smuga, Jakub; Pisarska, Anna; Kucharska, Małgorzata; Wesołowski, Wiktor

DOI:

Abstract

2-Methoxypropan-1-ol (2M1P) is a colorless, flammable liquid with an irritating effect. It is a primary alcohol formed as a by-product in the production of propylene glycol monomethyl ether (1-methoxypropan-2-ol). Therefore, exposure to this substance is inextricably connected with exposure to 1-methoxypropan-2-ol which is used as a solvent for paints, varnishes, dyes, etc., and as a component of cleaning preparations and an intermediate for chemical synthesis. In working environment, workers may be exposed to the action of 2-methoxypropan-1-ol by inhalation and dermal route. The aim of this study was to develop and validate a method for determining 2-methoxypropan-1-ol in workplace air. The developed method of 2M1P determination consists in adsorption of vapors of this substance on coconut shell charcoal, extraction with a solution of methanol in carbon disulfide and chromatographic analysis of the obtained solution. The study was performed with gas chromatograph coupled with mass spectrometer (GC-MS), equipped with a polar ZB-WAXplus capillary column (length 60 m, diameter 0.25 mm and the film thickness of the stationary phase 0.5 µm). The developed method is linear in the concentration range of 10.0-400.0 µg/ml, which corresponds to the range of 1.0-40.0 mg/m3 for a 10-L air sample.The analytical method described in this paper makes it possible to determine 2-methoxypropan-1-ol in workplace air in the presence of comorbid substances. This method is precise, accurate and it meets the criteria for procedure for determining chemical agents listed in Standard No. PN-EN 482. The developed method of determination of 2-methoxypropan-1-ol in workplace air has been recorded as an analytical procedure (see Appendix). This article discusses the problems of occupational safety and health, which are covered by health sciences and environmental engineering.

Keywords

2-methoxypropan-1-ol ; analytical method ; air at workplaces ; gas chromatographic method with mass spectrometry ; health sciences ; environmental engineering

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2-Methoxypropan-1-ol

12.0/5g

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