Products Cited in Publications Worldwide Photoiniferter RAFT Polymerization of Optically Active Hydrophilic Vitamin B5 Analogous Methacrylamide

Photoiniferter RAFT Polymerization of Optically Active Hydrophilic Vitamin B5 Analogous Methacrylamide

Combita, Diego; Pamunuwegedara, Randima; Ahmed, Marya

DOI:

Abstract

Chiroptical polymers are interesting due to diverse applications in the field of chromatog., biomedicines, and catalysis. This study describes the synthesis of new types of optically active polymers of vitamin B5 analogous methacrylamide (B5AMA) using a photoiniferter polymerization approach at ambient temperatures Enantiomers of B5AMA monomer ((R) and (S)) were prepared by the ring opening method and were characterized for their optical activity. The monomers were then polymerized by a photoiniferter polymerization approach using two different thiocarbonylthio (TCT) compounds as iniferters. Both TCTs showed controlled polymerization of B5AMA enantiomers and yielded polymers of opposite optical rotation. The enantiomeric polymers of B5AMA exhibited a complementary mirror-image Cotton effect to each other in the CD (CD) spectra, and 13C NMR anal. revealed the formation of syndiotactic polymer structures. To the best of our knowledge, this is the first study that depicts the successful synthesis of optically active macromols. by a photoiniferter polymerization approach.

Keywords

enantiomers ; photoiniferter polymerization ; polymer tacticity ; optically active polymers ; random coil structure ; pendant group chirality

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