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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 143621-35-6 Chemical Structure| 143621-35-6

Structure of Triapine
CAS No.: 143621-35-6

Chemical Structure| 143621-35-6

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Triapine is a ribonucleotide reductase inhibitor and a CDK inhibtor.

Synonyms: 3-AP; PAN-811; NSC663249. PAN-811

4.5 *For Research Use Only !

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Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

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Product Details of Triapine

CAS No. :143621-35-6
Formula : C7H9N5S
M.W : 195.24
SMILES Code : NC1=CC=CN=C1/C=N/NC(N)=S
Synonyms :
3-AP; PAN-811; NSC663249. PAN-811
MDL No. :MFCD00924747

Safety of Triapine

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301
Precautionary Statements:P501-P270-P264-P301+P310+P330-P405
Class:6.1
UN#:2811
Packing Group:

Related Pathways of Triapine

DNA

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT02644122 - Terminated(Slow enrollment) - -
NCT02644122 Metastatic Squamous Neck Cance... More >>r With Occult Primary Squamous Cell Carcinoma Less << Phase 2 Terminated(Slow enrollment) - United States, California ... More >> UC San Diego Moores Cancer Center La Jolla, California, United States, 92093 Less <<
NCT00024323 Unspecified Adult Solid Tumor,... More >> Protocol Specific Less << Phase 1 Completed - United States, Arizona ... More >> Arizona Clinical Research Center Tucson, Arizona, United States, 85712 United States, Connecticut Yale Comprehensive Cancer Center New Haven, Connecticut, United States, 06520-8028 Less <<
NCT01095731 Aneurysmal Subarachnoid Hemorr... More >>hage Less << Phase 2 Completed - United States, Florida ... More >> University of Florida Gainesville, Florida, United States, 32611 United States, New York Columbia University Medical Center New York, New York, United States, 10032 United States, Washington University of Washington Seattle, Washington, United States, 96104 Less <<
NCT00355654 Infant Health... More >>y Less << Phase 3 Completed - -
NCT00016874 Unspecified Adult Solid Tumor,... More >> Protocol Specific Less << Phase 1 Completed - United States, New York ... More >> Albert Einstein Comprehensive Cancer Center Bronx, New York, United States, 10461 New York Presbyterian Hospital - Cornell Campus New York, New York, United States, 10021 Less <<
NCT00064064 Lung Cancer Phase 2 Completed - United States, Illinois ... More >> University of Chicago Cancer Research Center Chicago, Illinois, United States, 60637-1470 United States, Minnesota University of Minnesota Cancer Center Minneapolis, Minnesota, United States, 55455 United States, Tennessee Sarah Cannon Cancer Center at Centennial Medical Center Nashville, Tennessee, United States, 37203 United States, Texas University of Texas - MD Anderson Cancer Center Houston, Texas, United States, 77030-4009 Netherlands University Medical Center Nijmegen Nijmegen, Netherlands, NL-6500 HB Less <<
NCT00004213 Unspecified Adult Solid Tumor,... More >> Protocol Specific Less << Phase 1 Completed - United States, Arizona ... More >> Arizona Clinical Research Center Tucson, Arizona, United States, 85712 United States, Connecticut Yale Comprehensive Cancer Center New Haven, Connecticut, United States, 06520-8028 Less <<
NCT00077558 Leukemia Myel... More >>odysplastic Syndromes Myelodysplastic/Myeloproliferative Diseases Less << Phase 1 Completed - United States, Georgia ... More >> Blood and Marrow Transplant Group of Georgia Atlanta, Georgia, United States, 30342-4777 United States, Maryland Greenebaum Cancer Center at University of Maryland Medical Center Baltimore, Maryland, United States, 21201 Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland, United States, 21231 United States, Texas M.D. Anderson Cancer Center at University of Texas Houston, Texas, United States, 77030-4095 Less <<
NCT00064090 Leukemia Myel... More >>odysplastic Syndromes Myelodysplastic/Myeloproliferative Neoplasms Less << Phase 1 Completed - United States, Texas ... More >> University of Texas - MD Anderson Cancer Center Houston, Texas, United States, 77030-4095 Less <<
NCT00054015 Prostate Cancer Phase 2 Completed - United States, California ... More >> UCSF Comprehensive Cancer Center San Francisco, California, United States, 94115 United States, Florida H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida, United States, 33612-9497 Less <<
NCT00064051 Pancreatic Cancer Phase 2 Completed - United States, Illinois ... More >> University of Chicago Cancer Research Center Chicago, Illinois, United States, 60637-1470 United States, Indiana Indiana Oncology Hematology Consultants Indianapolis, Indiana, United States, 46202 United States, Minnesota University of Minnesota Cancer Center Minneapolis, Minnesota, United States, 55455 United States, Tennessee Sarah Cannon Cancer Center at Centennial Medical Center Nashville, Tennessee, United States, 37203 Belgium Universitair Ziekenhuis Gent Ghent, Belgium, B-9000 United Kingdom Christie Hospital N.H.S. Trust Manchester, England, United Kingdom, M20 4BX Royal Marsden NHS Foundation Trust - Surrey Sutton, England, United Kingdom, SM2 5PT Less <<
NCT00075660 Kidney Cancer Phase 2 Completed - Canada, Alberta ... More >> Cross Cancer Institute Edmonton, Alberta, Canada, T6G 1Z2 Canada, British Columbia British Columbia Cancer Agency Vancouver, British Columbia, Canada, V5Z 4E6 Canada, Manitoba CancerCare Manitoba Winnipeg, Manitoba, Canada, R3E 0V9 Canada, Ontario Margaret and Charles Juravinski Cancer Centre Hamilton, Ontario, Canada, L8V 5C2 Cancer Care Ontario-London Regional Cancer Centre London, Ontario, Canada, N6A 4L6 Toronto Sunnybrook Regional Cancer Centre Toronto, Ontario, Canada, M4N 3M5 Toronto General Hospital Toronto, Ontario, Canada, M5G 2C4 Canada, Quebec Centre Hospitalier de l'Universite de Montreal Montreal, Quebec, Canada, H2L-4M1 Less <<
NCT00006218 Unspecified Adult Solid Tumor,... More >> Protocol Specific Less << Phase 1 Completed - United States, New York ... More >> Albert Einstein Comprehensive Cancer Center Bronx, New York, United States, 10461 Less <<
NCT00077415 Lung Cancer Phase 2 Completed - Australia, New South Wales ... More >> Sydney Cancer Centre at Royal Prince Alfred Hospital Sydney, New South Wales, Australia, 2050 Australia, Western Australia Sir Charles Gairdner Hospital - Perth Perth, Western Australia, Australia, 6009 Hong Kong Prince of Wales Hospital Shatin, New Territories, Hong Kong Korea, Republic of Yonsei Cancer Center at Yonsei University Medical Center Seoul, Korea, Republic of, 120-752 Singapore Cancer Institute at National University Hospital Singapore, Singapore, 119074 National University of Singapore Singapore, Singapore, 119260 National Cancer Centre - Singapore Singapore, Singapore, 169610 Johns Hopkins Singapore International Medical Centre Singapore, Singapore, 308433 Less <<
NCT00084877 Unspecified Adult Solid Tumor,... More >> Protocol Specific Less << Phase 1 Completed - United States, Wisconsin ... More >> University of Wisconsin Hospital and Clinics Madison, Wisconsin, United States, 53792 Less <<
NCT00381550 Accelerated Phase Chronic Myel... More >>ogenous Leukemia Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative Blastic Phase Chronic Myelogenous Leukemia Chronic Eosinophilic Leukemia Chronic Myelomonocytic Leukemia Essential Thrombocythemia Philadelphia Chromosome Negative Chronic Myelogenous Leukemia Polycythemia Vera Primary Myelofibrosis Relapsing Chronic Myelogenous Leukemia Less << Phase 2 Completed - United States, Maryland ... More >> Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore, Maryland, United States, 21287 Less <<
NCT00079014 Unspecified Adult Solid Tumor,... More >> Protocol Specific Less << Phase 1 Completed - United States, Wisconsin ... More >> University of Wisconsin Hospital and Clinics Madison, Wisconsin, United States, 53792 Less <<
NCT00081276 Primary Peritoneal Cavity Canc... More >>er Recurrent Ovarian Epithelial Cancer Stage III Ovarian Epithelial Cancer Stage IV Ovarian Epithelial Cancer Less << Phase 2 Completed - United States, Pennsylvania ... More >> Gynecologic Oncology Group Philadelphia, Pennsylvania, United States, 19103 Less <<
NCT00078975 Pancreatic Cancer Phase 2 Completed - Canada, Ontario ... More >> Margaret and Charles Juravinski Cancer Centre Hamilton, Ontario, Canada, L8V 5C2 London Regional Cancer Program at London Health Sciences Centre London, Ontario, Canada, N6A 4L6 Ottawa Hospital Regional Cancer Centre - General Campus Ottawa, Ontario, Canada, K1H 1C4 Princess Margaret Hospital Toronto, Ontario, Canada, M5G 2M9 Less <<
NCT00381550 - Completed - -
NCT00941070 Recurrent Cervical Cancer ... More >> Recurrent Vaginal Cancer Stage IB Cervical Cancer Stage II Vaginal Cancer Stage IIA Cervical Cancer Stage IIB Cervical Cancer Stage III Cervical Cancer Stage III Vaginal Cancer Stage IVA Cervical Cancer Stage IVA Vaginal Cancer Stage IVB Cervical Cancer Stage IVB Vaginal Cancer Therapy-related Toxicity Less << Phase 2 Completed - United States, Ohio ... More >> Case Western Reserve University Cleveland, Ohio, United States, 44106 Less <<
NCT00077545 Adenocarcinoma of the Esophagu... More >>s Recurrent Esophageal Cancer Stage IV Esophageal Cancer Less << Phase 2 Completed - United States, Illinois ... More >> University of Chicago Comprehensive Cancer Center Chicago, Illinois, United States, 60637-1470 Less <<
NCT00941070 - Completed - -
NCT00077181 Accelerated Phase Chronic Myel... More >>ogenous Leukemia Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) Adult Acute Myeloid Leukemia With t(15;17)(q22;q12) Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) Blastic Phase Chronic Myelogenous Leukemia Recurrent Adult Acute Lymphoblastic Leukemia Recurrent Adult Acute Myeloid Leukemia Relapsing Chronic Myelogenous Leukemia Secondary Acute Myeloid Leukemia Less << Phase 1 Completed - United States, Illinois ... More >> University of Chicago Comprehensive Cancer Center Chicago, Illinois, United States, 60637-1470 Less <<
NCT02466971 Cervical Adenocarcinoma ... More >> Cervical Adenosquamous Carcinoma Cervical Squamous Cell Carcinoma, Not Otherwise Specified Stage IB2 Cervical Cancer AJCC v6 and v7 Stage II Cervical Cancer AJCC v7 Stage II Vaginal Cancer AJCC v6 and v7 Stage IIA Cervical Cancer AJCC v7 Stage IIB Cervical Cancer AJCC v6 and v7 Stage III Vaginal Cancer AJCC v6 and v7 Stage IIIB Cervical Cancer AJCC v6 and v7 Stage IVA Cervical Cancer AJCC v6 and v7 Stage IVA Vaginal Cancer AJCC v6 and v7 Vaginal Adenocarcinoma Vaginal Adenosquamous Carcinoma Vaginal Squamous Cell Carcinoma, Not Otherwise Specified Less << Phase 2 Recruiting September 30, 2018 -
NCT00085371 Acinar Cell Adenocarcinoma of ... More >>the Pancreas Duct Cell Adenocarcinoma of the Pancreas Recurrent Pancreatic Cancer Stage III Pancreatic Cancer Stage IV Pancreatic Cancer Less << Phase 2 Completed - United States, Minnesota ... More >> Mayo Clinic Rochester, Minnesota, United States, 55905 Less <<
NCT00288093 Pancreatic Adenocarcinoma ... More >> Stage III Pancreatic Cancer AJCC v6 and v7 Less << Phase 1 Completed - United States, Ohio ... More >> Ohio State University Comprehensive Cancer Center Columbus, Ohio, United States, 43210 Less <<
NCT00095888 Male Breast Cancer ... More >> Recurrent Breast Cancer Stage IV Breast Cancer Less << Phase 2 Terminated(Administratively co... More >>mplete.) Less << - United States, Minnesota ... More >> Mayo Clinic Rochester, Minnesota, United States, 55905 Less <<
NCT00335998 Recurrent Cervical Cancer ... More >> Recurrent Ovarian Epithelial Cancer Recurrent Vaginal Cancer Recurrent Vulvar Cancer Stage III Vaginal Cancer Stage IIIA Cervical Cancer Stage IIIA Ovarian Epithelial Cancer Stage IIIA Vulvar Cancer Stage IIIB Cervical Cancer Stage IIIB Ovarian Epithelial Cancer Stage IIIB Vulvar Cancer Stage IIIC Ovarian Epithelial Cancer Stage IIIC Vulvar Cancer Stage IV Ovarian Epithelial Cancer Stage IVA Cervical Cancer Stage IVA Vaginal Cancer Stage IVB Cervical Cancer Stage IVB Vaginal Cancer Less << Phase 1 Completed - United States, Ohio ... More >> Case Western Reserve University Cleveland, Ohio, United States, 44106 Less <<
NCT00293345 Anaplastic Large Cell Lymphoma... More >> Angioimmunoblastic T-cell Lymphoma Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue Intraocular Lymphoma Nodal Marginal Zone B-cell Lymphoma Primary Central Nervous System Hodgkin Lymphoma Primary Central Nervous System Non-Hodgkin Lymphoma Recurrent Adult Burkitt Lymphoma Recurrent Adult Diffuse Large Cell Lymphoma Recurrent Adult Diffuse Mixed Cell Lymphoma Recurrent Adult Diffuse Small Cleaved Cell Lymphoma Recurrent Adult Hodgkin Lymphoma Recurrent Adult Immunoblastic Large Cell Lymphoma Recurrent Adult Lymphoblastic Lymphoma Recurrent Adult T-cell Leukemia/Lymphoma Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma Recurrent Grade 1 Follicular Lymphoma Recurrent Grade 2 Follicular Lymphoma Recurrent Grade 3 Follicular Lymphoma Recurrent Mantle Cell Lymphoma Recurrent Marginal Zone Lymphoma Recurrent Mycosis Fungoides/Sezary Syndrome Recurrent Small Lymphocytic Lymphoma Small Intestine Lymphoma Splenic Marginal Zone Lymphoma Stage III Adult Burkitt Lymphoma Stage III Adult Diffuse Large Cell Lymphoma Stage III Adult Diffuse Mixed Cell Lymphoma Stage III Adult Diffuse Small Cleaved Cell Lymphoma Stage III Adult Hodgkin Lymphoma Stage III Adult Immunoblastic Large Cell Lymphoma Stage III Adult Lymphoblastic Lymphoma Stage III Adult T-cell Leukemia/Lymphoma Stage III Cutaneous T-cell Non-Hodgkin Lymphoma Stage III Grade 1 Follicular Lymphoma Stage III Grade 2 Follicular Lymphoma Stage III Grade 3 Follicular Lymphoma Stage III Mantle Cell Lymphoma Stage III Marginal Zone Lymphoma Stage III Mycosis Fungoides/Sezary Syndrome Stage III Small Lymphocytic Lymphoma Stage IV Adult Burkitt Lymphoma Stage IV Adult Diffuse Large Cell Lymphoma Stage IV Adult Diffuse Mixed Cell Lymphoma Stage IV Adult Diffuse Small Cleaved Cell Lymphoma Stage IV Adult Hodgkin Lymphoma Stage IV Adult Immunoblastic Large Cell Lymphoma Stage IV Adult Lymphoblastic Lymphoma Stage IV Adult T-cell Leukemia/Lymphoma Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma Stage IV Grade 1 Follicular Lymphoma Stage IV Grade 2 Follicular Lymphoma Stage IV Grade 3 Follicular Lymphoma Stage IV Mantle Cell Lymphoma Stage IV Marginal Zone Lymphoma Stage IV Mycosis Fungoides/Sezary Syndrome Stage IV Small Lymphocytic Lymphoma Unspecified Adult Solid Tumor, Protocol Specific Waldenstr?m Macroglobulinemia Less << Phase 1 Completed - United States, Ohio ... More >> Ohio State University Medical Center Columbus, Ohio, United States, 43210 Less <<
NCT02595879 Cervical Adenocarcinoma ... More >> Cervical Adenosquamous Carcinoma Cervical Squamous Cell Carcinoma, Not Otherwise Specified Stage IB Vulvar Cancer AJCC v7 Stage IB2 Cervical Cancer AJCC v6 and v7 Stage II Vulvar Cancer AJCC v7 Stage IIA1 Cervical Cancer AJCC v7 Stage IIA2 Cervical Cancer AJCC v7 Stage IIB Cervical Cancer AJCC v6 and v7 Stage IIIA Cervical Cancer AJCC v6 and v7 Stage IIIA Vulvar Cancer AJCC v7 Stage IIIB Cervical Cancer AJCC v6 and v7 Stage IIIB Vulvar Cancer AJCC v7 Stage IIIC Vulvar Cancer AJCC v7 Stage IVA Cervical Cancer AJCC v6 and v7 Stage IVA Vulvar Cancer AJCC v7 Vulvar Adenocarcinoma Vulvar Squamous Cell Carcinoma Less << Phase 1 Suspended(Drug Supply Issues) - United States, Pennsylvania ... More >> University of Pittsburgh Cancer Institute (UPCI) Pittsburgh, Pennsylvania, United States, 15232 United States, Virginia University of Virginia Cancer Center Charlottesville, Virginia, United States, 22908 Less <<
NCT00077350 Recurrent Non-small Cell Lung ... More >>Cancer Less << Phase 2 Completed - United States, Massachusetts ... More >> Eastern Cooperative Oncology Group Boston, Massachusetts, United States, 02215 Less <<
NCT00075504 Stage II Gallbladder Cancer ... More >> Stage IIIA Gallbladder Cancer Stage IIIB Gallbladder Cancer Stage IVA Gallbladder Cancer Stage IVB Gallbladder Cancer Less << Phase 2 Completed - United States, New York ... More >> Montefiore Medical Center Bronx, New York, United States, 10467-2490 Less <<
NCT00390052 Unspecified Adult Solid Tumor,... More >> Protocol Specific Less << Phase 1 Completed - United States, California ... More >> City of Hope Duarte, California, United States, 91010 Less <<
NCT00075504 - Completed - -

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

5.12mL

1.02mL

0.51mL

25.61mL

5.12mL

2.56mL

51.22mL

10.24mL

5.12mL

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