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Chemical Structure| 1293281-49-8 Chemical Structure| 1293281-49-8

Structure of Seltorexant
CAS No.: 1293281-49-8

Chemical Structure| 1293281-49-8

Seltorexant

CAS No.: 1293281-49-8

Seltorexant is a selective orexin-2 receptor antagonist that has been shown to promote sleep in various species.

Synonyms: JNJ-42847922

4.5 *For Research Use Only !

Cat. No.: A407757 Purity: 99%

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Product Details of Seltorexant

CAS No. :1293281-49-8
Formula : C21H22FN7O
M.W : 407.44
SMILES Code : CC1=NC(N(CC2C3)CC2CN3C(C4=C(N5N=CC=N5)C=CC=C4F)=O)=NC(C)=C1
Synonyms :
JNJ-42847922
MDL No. :MFCD31700700

Safety of Seltorexant

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT05236868 Healthy PHASE1 COMPLETED 2022-03-01 PRA Health Sciences Onderzoeks... More >>centrum Groningen, locatie Martini, Groningen, 9728 NZ, Netherlands Less <<
NCT04616677 Renal Impairment PHASE1 COMPLETED 2022-10-18 Orlando Clinical Research Cent... More >>er, Orlando, Florida, 32809, United States|AMR New Orleans, Formerly New Orleans Center for Clinical Research - New Orleans, an AMR company, Knoxville, Tennessee, 37923, United States Less <<
NCT04960124 Healthy|Hepatic Impairment PHASE1 COMPLETED 2021-11-19 CRS Clinical Research Services... More >> Kiel GmbH, Kiel, 24105, Germany|APEX GmbH, Munchen, 81241, Germany Less <<
NCT04553042 Healthy PHASE1 COMPLETED 2020-12-30 PRA Health Sciences, Salt Lake... More >> City, Utah, 84124, United States Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.45mL

0.49mL

0.25mL

12.27mL

2.45mL

1.23mL

24.54mL

4.91mL

2.45mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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