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Chemical Structure| 481-42-5 Chemical Structure| 481-42-5

Structure of Plumbagin
CAS No.: 481-42-5

Chemical Structure| 481-42-5

Plumbagin

CAS No.: 481-42-5

Plumbagin is an anticancer agent, induces G2/M cell cycle arrest and apoptosis in A549 cells through JNK-dependentp53 Ser15 phosphorylation and inhibits A549 and MDA-MD-231 tumour xenograft growth in nude mice.

Synonyms: 2-Methyljuglone; NSC 236613; NSC 688284

4.5 *For Research Use Only !

Cat. No.: A187738 Purity: 98%

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Product Details of Plumbagin

CAS No. :481-42-5
Formula : C11H8O3
M.W : 188.18
SMILES Code : O=C(C1=C2C=CC=C1O)C=C(C)C2=O
Synonyms :
2-Methyljuglone; NSC 236613; NSC 688284
InChI Key :VCMMXZQDRFWYSE-UHFFFAOYSA-N
Pubchem ID :10205

Safety of Plumbagin

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P280-P305+P351+P338

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

5.31mL

1.06mL

0.53mL

26.57mL

5.31mL

2.66mL

53.14mL

10.63mL

5.31mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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