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Chemical Structure| 260415-63-2 Chemical Structure| 260415-63-2

Structure of PD173955
CAS No.: 260415-63-2

Chemical Structure| 260415-63-2

PD173955

CAS No.: 260415-63-2

PD173955 is ansrc family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase and is less potent for FGFRα and no activity on InsR and PKC.

Synonyms: PD173955

4.5 *For Research Use Only !

Cat. No.: A436930 Purity: 99%

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Product Details of PD173955

CAS No. :260415-63-2
Formula : C21H16Cl2N4OS
M.W : 443.35
SMILES Code : O=C1C(C2=C(Cl)C=CC=C2Cl)=CC3=CN=C(NC4=CC=CC(SC)=C4)N=C3N1C
Synonyms :
PD173955
MDL No. :MFCD16038305

Safety of PD173955

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Related Pathways of PD173955

RTK

Isoform Comparison

Biological Activity

Target
  • Bcr-Abl

    Bcr-Abl, IC50:1 nM-2 nM

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.26mL

0.45mL

0.23mL

11.28mL

2.26mL

1.13mL

22.56mL

4.51mL

2.26mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

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