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Chemical Structure| 61869-08-7 Chemical Structure| 61869-08-7

Structure of Paroxetine
CAS No.: 61869-08-7

Chemical Structure| 61869-08-7

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Paroxetine is an orally active selective serotonin reuptake inhibitor (SSRI) and a very weak norepinephrine (NE) reuptake inhibitor. It has antidepressant, anxiolytic, and analgesic effects and is used to treat obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and chronic headaches.

Synonyms: BRL29060

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Product Details of Paroxetine

CAS No. :61869-08-7
Formula : C19H20FNO3
M.W : 329.37
SMILES Code : FC1=CC=C([C@H]2[C@H](COC3=CC=C(OCO4)C4=C3)CNCC2)C=C1
Synonyms :
BRL29060
MDL No. :MFCD00869588

Safety of Paroxetine

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00839397 Post-Traumatic Stress Disorder PHASE3 COMPLETED 2025-06-05 -
NCT00620581 Premenstrual Dysphoric Disorde... More >>r Less << PHASE3 COMPLETED - Women's Health Concerns Clinic... More >>, Hamilton, Ontario, L8N 4A6, Canada Less <<
NCT01371435 Mental Disorders COMPLETED 2025-12-05 -
NCT00357045 Major Depression PHASE4 COMPLETED - -
NCT01371448 Mental Disorders COMPLETED 2025-09-05 -
NCT00700999 Post-traumatic Stress Disorder PHASE4 COMPLETED 2025-03-12 Jesse Brown VA Medical Center ... More >>Community-Based Outpatient Clinic Lake Side Divison, Chicago, IL, Chicago, Illinois, 60611, United States|Jesse Brown VA Medical Center, Chicago, IL, Chicago, Illinois, 60612, United States|VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor, Michigan, 48113, United States Less <<
NCT00196664 Chronic Hepatitis C PHASE3 COMPLETED 2025-02-09 Service d'Hépato-gastroentérol... More >>ogie CHU de Nancy, Vandoeuvre, 54500, France Less <<
NCT01371461 Mental Disorders COMPLETED 2025-10-04 -
NCT05725837 Septic Shock|Sepsis PHASE2 RECRUITING 2025-04-15 Hospital Maternidade S?o José ... More >>de Colatina, Colatina, Espirito Santo, Brazil|Hospital S?o José, Criciúma, Santa Catarina, 88801460, Brazil Less <<
NCT01371474 Panic Disorder COMPLETED 2025-06-08 -
NCT01376271 Social Phobia COMPLETED 2025-09-13 -
NCT06065735 Anxiety Disorders PHASE1 COMPLETED 2024-01-08 GSK Investigational Site, Lond... More >>on, HA1 3UJ, United Kingdom Less <<
NCT03894085 Anxiety Disorder|Obsessive-Com... More >>pulsive Disorder Less << COMPLETED 2022-12-31 The Second Xiangya Hospital of... More >> Central South University, Changsha, China Less <<
NCT01376128 Panic Disorder COMPLETED 2025-05-09 -
NCT00403455 PTSD PHASE3 COMPLETED 2025-07-11 Ralph H. Johnson VA Medical Ce... More >>nter, Charleston, SC, Charleston, South Carolina, 29401-5799, United States Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.04mL

0.61mL

0.30mL

15.18mL

3.04mL

1.52mL

30.36mL

6.07mL

3.04mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
 

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