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Chemical Structure| 1394820-69-9 Chemical Structure| 1394820-69-9

Structure of Ningetinib
CAS No.: 1394820-69-9

Chemical Structure| 1394820-69-9

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Ningetinib is an inhibitor of tyrosine kinase inhibitor (TKI) and the IC50 for c-Met, VEGFR2 and Axl are 6.7 nM, 1.9 nM and <1.0 nM respectively.

Synonyms: CT-053; DE-120; CT053 free base

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Product Details of Ningetinib

CAS No. :1394820-69-9
Formula : C31H29FN4O5
M.W : 556.58
SMILES Code : O=C(C1=C(C)N(C)N(C2=CC=CC=C2)C1=O)NC3=CC=C(OC4=CC=NC5=CC(OCC(C)(O)C)=CC=C45)C(F)=C3
Synonyms :
CT-053; DE-120; CT053 free base
MDL No. :MFCD28502048
InChI Key :VQYYQSZNRVQLIS-UHFFFAOYSA-N
Pubchem ID :60165029

Safety of Ningetinib

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of Ningetinib

RTK

Isoform Comparison

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1 mM

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1.80mL

0.36mL

0.18mL

8.98mL

1.80mL

0.90mL

17.97mL

3.59mL

1.80mL

 

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