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Chemical Structure| 1201902-80-8 Chemical Structure| 1201902-80-8

Structure of MLN9708
CAS No.: 1201902-80-8

Chemical Structure| 1201902-80-8

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MLN9708 is the prodrug of MLN2238 which is an inhibitor of the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50 and Ki of 3.4 nM, 0.93 nM, respectively.

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Product Details of MLN9708

CAS No. :1201902-80-8
Formula : C20H23BCl2N2O9
M.W : 517.12
SMILES Code : O=C(C(C1)(CC(O)=O)OB([C@@H](NC(CNC(C2=CC(Cl)=CC=C2Cl)=O)=O)CC(C)C)OC1=O)O
InChI Key :YTXSYWAKVMZICI-PVCZSOGJSA-N
Pubchem ID :49867936

Safety of MLN9708

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

Target
  • 20S proteasome

    20S proteasome, IC50:3.4 nM

    20S proteasome, Ki:0.93 nM

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.93mL

0.39mL

0.19mL

9.67mL

1.93mL

0.97mL

19.34mL

3.87mL

1.93mL

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