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Chemical Structure| 103745-39-7 Chemical Structure| 103745-39-7

Structure of Fasudil
CAS No.: 103745-39-7

Chemical Structure| 103745-39-7

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Fasudil HCl is a potent inhibitor of ROCK-II, PKA, PKG, PKC, and MLCK with Ki of 0.33 μM, 1.6 μM, 1.6 μM, 3.3 μM and 36 μM, respectively.

Synonyms: AT877; HA-1077

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Product Details of Fasudil

CAS No. :103745-39-7
Formula : C14H17N3O2S
M.W : 291.37
SMILES Code : O=S(C1=CC=CC2=C1C=CN=C2)(N3CCNCCC3)=O
Synonyms :
AT877; HA-1077
MDL No. :MFCD00866182

Safety of Fasudil

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P261-P305+P351+P338

Related Pathways of Fasudil

epigenetics
cytoskeleton
Hedgehog

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT01069042 Heart Failure Phase 4 Unknown November 2010 Taiwan ... More >> National Cheng Kung University Hospital Recruiting Tainan, Taiwan, 70401 Contact: Ping-Yen Liu, MD, PhD Less <<
NCT03404843 Cardiovascular Diseases Phase 2 Completed - United States, Colorado ... More >> Colorado State University, Dept. of Health and Exercise Science Fort Collins, Colorado, United States, 80523 Less <<
NCT01823081 Diabetic Macular Edema Phase 3 Completed - Iran, Islamic Republic of ... More >> Tehran, Iran, Islamic Republic of Less <<
NCT00670202 Carotid Stenosis Phase 2 Terminated(Slow enrollment) - United States, Massachusetts ... More >> Brigham and Women's Hospital Boston, Massachusetts, United States, 02115 Less <<
NCT00498615 Raynaud Scler... More >>oderma Less << Phase 3 Completed - United States, Maryland ... More >> Johns Hopkins University Baltimore, Maryland, United States, 21224 Less <<
NCT03391219 Retinal Vein Occlusion Phase 2 Phase 3 Recruiting October 2018 Iran, Islamic Republic of ... More >> Ophthalmic Research Center Recruiting Tehran, Iran, Islamic Republic of Contact: Ramin Noorinia, MD    009822591616    labbafi@hotmail.com Less <<
NCT00670202 - Terminated(Slow enrollment) - -
NCT01935518 Amyotrophic Lateral Sclerosis Phase 2 Unknown May 2015 China ... More >> Peking University Third Hospital Recruiting Beijing, China, 100191 Contact: Xiaolu Liu, MD    0086-1082265032    liuxiaolupku@gmail.com    Principal Investigator: Dongsheng Fan, MD, PhD Less <<
NCT00498615 - Completed - -
NCT00120718 Atherosclerosis ... More >> Hypercholesterolemia Less << Phase 2 Completed - United States, Massachusetts ... More >> Brigham and Women's Hospital Boston, Massachusetts, United States, 02115 Less <<
NCT03753269 ST Segment Elevation Myocardia... More >>l Infarction Less << Phase 4 Not yet recruiting December 30, 2022 -

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.43mL

0.69mL

0.34mL

17.16mL

3.43mL

1.72mL

34.32mL

6.86mL

3.43mL

References

 

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