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Chemical Structure| 70384-83-7 Chemical Structure| 70384-83-7
Chemical Structure| 70384-83-7

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Product Details of Ethyl 5-chloro-2-oxo-2H-chromene-3-carboxylate

CAS No. :70384-83-7
Formula : C12H9ClO4
M.W : 252.65
SMILES Code : O=C(C(C1=O)=CC2=C(O1)C=CC=C2Cl)OCC
MDL No. :MFCD27952738
InChI Key :OOBBQYYHHVMNHD-UHFFFAOYSA-N
Pubchem ID :20341477

Safety of Ethyl 5-chloro-2-oxo-2H-chromene-3-carboxylate

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of Ethyl 5-chloro-2-oxo-2H-chromene-3-carboxylate

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 70384-83-7 ]

[ 70384-83-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 110-89-4 ]
  • [ 18362-30-6 ]
  • [ 105-53-3 ]
  • 4-amino-9-chloro-2-methyl-1,2,3,4,4a,10a-hexahydro[10 H]benzopyrano[3,2-c]pyrid-10-ylacetic acid lactam [ No CAS ]
  • [ 70384-83-7 ]
YieldReaction ConditionsOperation in experiment
58% With acetic acid; In ethanol; EXAMPLE 19 4-amino-9-chloro-2-methyl-1,2,3,4,4a,10a-hexahydro[10 H]benzopyrano[3,2-c]pyrid-10-ylacetic acid lactam. C15 H17 ClN2 O2. Molecular weight=292.77. 19.1 Ethyl 5-chlorocoumarin-3-carboxylate C12 H9 ClO4. Molecular weight 252.5. 15 g (0.0958 mole) of <strong>[18362-30-6]2-chloro-6-hydroxy-benzaldehyde</strong>, 16.7 g (0.105 mole) ethyl malonate, 40 mL ethanol, 0.6 mL piperidine and 0.1 mL acetic acid are refluxed for 5 hours. After cooling the resultant product is dried. After drying, 14 g of ethyl 5-chlorocoumarin-3-carboxylate are obtained. (Yield=58percent). Melting pointG =142°-144° C. IRnuC=0: 1720 cm-1. C=0: 1760 cm-1. NMR (CDCl3)deltappm relative to TMS.
 

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