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Chemical Structure| 1010100-07-8 Chemical Structure| 1010100-07-8

Structure of CC-885
CAS No.: 1010100-07-8

Chemical Structure| 1010100-07-8

CC-885

CAS No.: 1010100-07-8

CC-885 is a novel cereblon (CRBN) modulator that promotes the ubiquitination and degradation of GSPT1 by recruiting it to the CRL4(CRBN) E3 ubiquitin ligase complex. CC-885 holds potential application value in cancer research, particularly in tumors dependent on specific protein stability.

4.5 *For Research Use Only !

Cat. No.: A799169 Purity: 99%

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Product Details of CC-885

CAS No. :1010100-07-8
Formula : C22H21ClN4O4
M.W : 440.88
SMILES Code : O=C(NCC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2)=O)C=C1)NC4=CC=C(C)C(Cl)=C4
MDL No. :MFCD31657329
InChI Key :DOEVCIHTTTYVCC-UHFFFAOYSA-N
Pubchem ID :24788636

Safety of CC-885

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Isoform Comparison

Biological Activity

Target
  • CRBN

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.27mL

0.45mL

0.23mL

11.34mL

2.27mL

1.13mL

22.68mL

4.54mL

2.27mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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