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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 81846-19-7 Chemical Structure| 81846-19-7

Structure of Treprostinil
CAS No.: 81846-19-7

Chemical Structure| 81846-19-7

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Rumodolinl, a analog of prostacyclin, is an agonist of IP receptor that used clinically to treat pulmonary arterial hypertension. It is a vasodilator with antithrombotic and anti-inflammatory properties.

Synonyms: UT-15; BW 15AU; Uniprost

4.5 *For Research Use Only !

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Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

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Product Details of Treprostinil

CAS No. :81846-19-7
Formula : C23H34O5
M.W : 390.51
SMILES Code : O=C(O)COC1=CC=CC2=C1C[C@]3([H])[C@]([C@@H](CC[C@@H](O)CCCCC)[C@H](O)C3)([H])C2
Synonyms :
UT-15; BW 15AU; Uniprost
MDL No. :MFCD00888847
InChI Key :PAJMKGZZBBTTOY-ZFORQUDYSA-N
Pubchem ID :6918140

Safety of Treprostinil

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H331-H361
Precautionary Statements:P501-P270-P202-P201-P264-P280-P308+P313-P362+P364-P301+P310+P330-P302+P352+P312-P405
Class:6.1
UN#:2811
Packing Group:

Related Pathways of Treprostinil

GPCR

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT01028651 Portopulmonary Hypertension|Pu... More >>lmonary Arterial Hypertension|Pulmonary Hypertension Less << COMPLETED 2025-04-13 University of California, Los ... More >>Angeles, Los Angeles, California, 90024, United States|Emory Univeristy, Atlanta, Georgia, 30322, United States|Brigham and Women's Hospital, Boston, Massachusetts, 02115, United States|University of Texas, Southwestern Medical Center, Dallas, Texas, 75235, United States Less <<
NCT02498444 Single Ventricle TERMINATED 2025-12-20 Lucile Packard Children's Hosp... More >>ital, Stanford, Palo Alto, California, 94304, United States Less <<
NCT04005469 Ischemia Reperfusion Injury|De... More >>layed Graft Function Less << PHASE1|PHASE2 RECRUITING 2026-06-30 Rhode Island Hospital, Provide... More >>nce, Rhode Island, 02903, United States Less <<
NCT00004497 Pulmonary Hypertension PHASE3 COMPLETED 2000-09-01 Los Angeles County Harbor-UCLA... More >> Medical Center, Torrance, California, 90509, United States|Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, 60612, United States|University of Maryland Medical System, Baltimore, Maryland, 21201, United States|Mayo Clinic, Rochester, Minnesota, 55905, United States|Columbia University College of Physicians and Surgeons, New York, New York, 10032, United States|United Therapeutics Corporation, Research Triangle Park, North Carolina, 27709, United States|Vanderbilt University Medical Center, Nashville, Tennessee, 37232-2516, United States Less <<
NCT00705133 Pulmonary Arterial Hypertensio... More >>n|Interstitial Lung Disease|Idiopathic Pulmonary Fibrosis Less << PHASE2 COMPLETED 2025-04-11 David Geffen School of Medicin... More >>e, UCLA, Los Angeles, California, 90095, United States Less <<
NCT03835676 Pulmonary Hypertension PHASE4 RECRUITING 2025-12-01 Aswan Heart Centre - Magdi Yac... More >>oub Heart Foundation, Aswan, Egypt Less <<
NCT06603285 Pulmonary Arterial Hypertensio... More >>n Less << NOT_YET_RECRUITING 2029-06-30 -
NCT01481974 Ischemia Reperfusion Injury PHASE1 COMPLETED 2019-11-24 Abhinav Humar, Pittsburgh, Pen... More >>nsylvania, 15261, United States|University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, 15261, United States Less <<
NCT01268553 Pulmonary Arterial Hypertensio... More >>n Less << PHASE4 COMPLETED 2016-10-05 University of Arizona, Tucson,... More >> Arizona, 85721, United States|University of CA, San Francisco, San Francisco, California, 94143, United States|Harbor-UCLA Medical Center, Torrance, California, 90502, United States Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.56mL

0.51mL

0.26mL

12.80mL

2.56mL

1.28mL

25.61mL

5.12mL

2.56mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

Historical Records

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