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Chemical Structure| 1374516-07-0 Chemical Structure| 1374516-07-0

Structure of TUG-891
CAS No.: 1374516-07-0

Chemical Structure| 1374516-07-0

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TUG-891 is a selective agonist of long chain free fatty acid (LCFA) receptor 4 (GPR120).

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Product Details of TUG-891

CAS No. :1374516-07-0
Formula : C23H21FO3
M.W : 364.41
SMILES Code : O=C(O)CCC1=CC=C(OCC2=CC(F)=CC=C2C3=CC=C(C)C=C3)C=C1
MDL No. :MFCD22421654
InChI Key :LPGBXHWIQNZEJB-UHFFFAOYSA-N
Pubchem ID :57522038

Safety of TUG-891

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of TUG-891

GPCR

Isoform Comparison

Biological Activity

In Vitro:

Cell Line
Concentration Treated Time Description References
Mouse colonic mucosal cells 300 nM 10–15 minutes To compare the pharmacology of FFA1 and FFA4 agonists, finding selective agonists more potent than GW9508 PMC5715575

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.74mL

0.55mL

0.27mL

13.72mL

2.74mL

1.37mL

27.44mL

5.49mL

2.74mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

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