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Chemical Structure| 39777-61-2 Chemical Structure| 39777-61-2

Structure of TFEB activator 1
CAS No.: 39777-61-2

Chemical Structure| 39777-61-2

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TFEB activator 1 is an orally effective, mTOR-independent activator of TFEB. It significantly promotes the nuclear translocation of Flag-TFEB with an EC50 of 2167 nM and enhances autophagy without inhibiting the mTOR pathway and has the potential for neurodegenerative diseases treatment. It also shows cytotoxic effect on HeLa, K562, MCF-​7 and MDA-​MB-​231 cancer cell lines.

Synonyms: Curcumin analog C1; GO-Y019; RPN77612

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Product Details of TFEB activator 1

CAS No. :39777-61-2
Formula : C19H18O3
M.W : 294.34
SMILES Code : O=C(/C=C/C1=CC=CC=C1OC)/C=C/C2=CC=CC=C2OC
Synonyms :
Curcumin analog C1; GO-Y019; RPN77612
MDL No. :MFCD00719180
InChI Key :RCZMPCUUTSDNAJ-PHEQNACWSA-N
Pubchem ID :830608

Safety of TFEB activator 1

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Isoform Comparison

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Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.40mL

0.68mL

0.34mL

16.99mL

3.40mL

1.70mL

33.97mL

6.79mL

3.40mL

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