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Chemical Structure| 541502-14-1 Chemical Structure| 541502-14-1

Structure of Siltuximab
CAS No.: 541502-14-1

Chemical Structure| 541502-14-1

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Siltuximab

CAS No.: 541502-14-1

,99%

Siltuximab is a humanized IgG1 monoclonal antibody that prevents IL-6 from binding to its receptor by binding to IL-6. Siltuximab has potential for research in multiple myeloma and Castleman disease.

Synonyms: CNTO-328

4.5 *For Research Use Only !

Cat. No.: A1616488 Purity: 99%

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    Product Details of Siltuximab

    CAS No. :541502-14-1
    M.W : 144.98 kDa
    SMILES Code : NONE
    Synonyms :
    CNTO-328

    Safety of Siltuximab

    GHS Pictogram:
    Signal Word:Warning
    Hazard Statements:H302-H315-H319
    Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

    Related Pathways of Siltuximab

    pyroptosis

    Isoform Comparison

    Biological Activity

    Clinical Trial:

    NCT Number Conditions Phases Recruitment Completion Date Locations
    NCT05316116 Large Granular Lymphocyte Leuk... More >>emia Less << EARLY_PHASE1 ACTIVE_NOT_RECRUITING 2027-11-17 Moffitt Cancer Center, Tampa, ... More >>Florida, 33612, United States Less <<
    NCT02641522 Type 1 Diabetes EARLY_PHASE1 COMPLETED 2017-03-16 Benaroya Research Institute, S... More >>eattle, Washington, 98101, United States Less <<
    NCT04975555 Cytokine Release Syndrome|ICAN... More >>S|Lymphoma, Non-Hodgkin|Multiple Myeloma|Acute Lymphoblastic Leukemia Less << PHASE2 RECRUITING 2027-12-31 University of Alabama at Birmi... More >>ngham, Birmingham, Alabama, 35294, United States Less <<
    NCT01309412 Multiple Myeloma PHASE1 TERMINATED 2025-12-12 Isehara, Japan|Kyoto, Japan|Na... More >>goya, Japan|Niigata, Japan|Tokyo, Japan Less <<
    NCT01400503 Multicentric Castleman's Disea... More >>se Less << PHASE2 COMPLETED 2017-03-01 Little Rock, Arkansas, United ... More >>States|Tampa, Florida, United States|Lansing, Michigan, United States|Chapel Hill, North Carolina, United States|Greenville, South Carolina, United States|Houston, Texas, United States|Seattle, Washington, United States|Leuven, Belgium|Sao Paulo, Brazil|Toronto, Canada|Beijing, China|Chengdu, China|Cairo, Egypt|Montpellier, France|Tours Cedex 9, France|Vandoeuvre Les Nancy, France|Berlin, Germany|Sha Tin, Hong Kong|Ramat Gan, Israel|Seoul, Korea, Republic of|Auckland, New Zealand|Oslo, Norway|Singapore, Singapore|Madrid, Spain|Taipei, Taiwan|Manchester, United Kingdom Less <<
    NCT04838860 Idiopathic Multicentric Castle... More >>man's Disease Less << PHASE2 TERMINATED 2021-04-01 Edward W. Sparrow Hospital, La... More >>nsing, Michigan, 48912, United States Less <<
    NCT05697510 Acute Myeloid Leukemia (AML) PHASE1 RECRUITING 2025-06-30 CHU de Nantes, Nantes, 44093, ... More >>France Less <<
     

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