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Chemical Structure| 135159-51-2 Chemical Structure| 135159-51-2

Structure of Sarpogrelate HCl
CAS No.: 135159-51-2

Chemical Structure| 135159-51-2

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Sarpogrelate HCl is an antagonist of both 5HT2A and 5-HT2B receptors, which can block serotonin-induced platelet aggregation and treat diabetes mellitus, Buerger's disease, Raynaud's disease, coronary artery disease, angina pectoris and atherosclerosis.

Synonyms: MCI-9042; Sarpogrelate (hydrochloride); Sarpogrelate hydrochloride

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Product Details of Sarpogrelate HCl

CAS No. :135159-51-2
Formula : C24H32ClNO6
M.W : 465.97
SMILES Code : O=C(OC(COC1=CC=CC=C1CCC2=CC=CC(OC)=C2)CN(C)C)CCC(O)=O.[H]Cl
Synonyms :
MCI-9042; Sarpogrelate (hydrochloride); Sarpogrelate hydrochloride
MDL No. :MFCD00887582
InChI Key :POQBIDFFYCYHOB-UHFFFAOYSA-N
Pubchem ID :444005

Safety of Sarpogrelate HCl

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H319-H332-H372-H400
Precautionary Statements:P260-P264-P270-P273-P280-P301+P312+P330-P304+P312-P305+P351+P338-P314-P337+P313-P391-P501
Class:9
UN#:3077
Packing Group:

Related Pathways of Sarpogrelate HCl

GPCR

Isoform Comparison

Biological Activity

Target
  • 5-HT2

    5-HT2A, Kd:2.1 nM

    5-HT2C, Kd:1.1 nM

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00147303 Cerebral Infarction PHASE3 COMPLETED 2025-01-05 -

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.15mL

0.43mL

0.21mL

10.73mL

2.15mL

1.07mL

21.46mL

4.29mL

2.15mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

References

 

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