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Chemical Structure| 1337532-29-2 Chemical Structure| 1337532-29-2

Structure of GSK2656157
CAS No.: 1337532-29-2

Chemical Structure| 1337532-29-2

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GSK2656157 displays selectivity and ATP-competitive inhibition against protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK), with an IC50 of 0.9 nM.

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Product Details of GSK2656157

CAS No. :1337532-29-2
Formula : C23H21FN6O
M.W : 416.45
SMILES Code : CC1=CC=CC(CC(N2CCC3=C2C=CC(C4=CN(C)C5=NC=NC(N)=C54)=C3F)=O)=N1
MDL No. :MFCD27997885
InChI Key :PRWSIEBRGXYXAJ-UHFFFAOYSA-N
Pubchem ID :53469059

Safety of GSK2656157

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Isoform Comparison

Biological Activity

Target
  • PERK

    PERK, IC50:0.9 nM

Protocol

Bio Calculators
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