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Chemical Structure| 2170722-84-4 Chemical Structure| 2170722-84-4

Structure of Emraclidine
CAS No.: 2170722-84-4

Chemical Structure| 2170722-84-4

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Emraclidine is a positive allosteric modulator of the muscarinic M4 receptor, suitable for research in neurological diseases, particularly demonstrating potential application in treatments for schizophrenia and Alzheimer’s disease.

Synonyms: CVL-231

4.5 *For Research Use Only !

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Product Details of Emraclidine

CAS No. :2170722-84-4
Formula : C20H21F3N4O
M.W : 390.40
SMILES Code : FC(C1=NC=CC(N2CC(CC(N3CC4=NC(C)=CC(C)=C4C3)=O)C2)=C1)(F)F
Synonyms :
CVL-231
MDL No. :MFCD34186088
InChI Key :DTCZNKWBDTXEBS-UHFFFAOYSA-N
Pubchem ID :140830653

Safety of Emraclidine

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT05915546 Healthy PHASE1 COMPLETED 2023-07-26 Dilworth, Minnesota, Dilworth,... More >> Minnesota, 56529, United States Less <<
NCT05935033 Hepatic Impairment PHASE1 RECRUITING 2024-12-23 Miami, Florida, Miami, Florida... More >>, 33136, United States|Orlando, Florida, Orlando, Florida, 32809, United States|San Antonio, Texas, San Antonio, Texas, 78215, United States Less <<
NCT05245539 Blood Pressure|Schizophrenia PHASE1 COMPLETED 2022-11-14 Pillar Clinical Research LLC, ... More >>Bentonville, Arkansas, 72712, United States|Woodland International Research Group LLC - ERG - PPDS, Little Rock, Arkansas, 72211, United States|Collaborative NeuroScience Research, LLC - Torrance - Apex - PPDS, Long Beach, California, 90806, United States|Innovative Clinical Research, Inc - ClinEdge - PPDS, Miami, Florida, 33016, United States|Uptown Research Institute LLC, Chicago, Illinois, 60640, United States|Pillar Clinical Research LLC, Lincolnwood, Illinois, 60712, United States|Hassman Research Institute - Apex - PPDS, Marlton, New Jersey, 08053, United States|Neuro-Behavioral Clinical Research, Inc., North Canton, Ohio, 44720, United States|Community Clinical Research, Austin, Texas, 78754, United States|Pillar Clinical Research LLC, Richardson, Texas, 75080, United States Less <<
NCT06301971 Healthy Participants PHASE1 COMPLETED 2024-04-04 Austin, Texas, Austin, Texas, ... More >>78744, United States Less <<
NCT05940402 Renal Impairment PHASE1 ACTIVE_NOT_RECRUITING 2025-06-01 Tustin, California, Tustin, Ca... More >>lifornia, 92780, United States|Miami, Florida, Miami, Florida, 33014, United States|Miami, Florida, Miami, Florida, 33136, United States|Orlando, Florida, Orlando, Florida, 32808, United States|Knoxville, Tennessee, Knoxville, Tennessee, 37920, United States Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.56mL

0.51mL

0.26mL

12.81mL

2.56mL

1.28mL

25.61mL

5.12mL

2.56mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
 

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