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Chemical Structure| 1257213-50-5 Chemical Structure| 1257213-50-5

Structure of BMS-986020
CAS No.: 1257213-50-5

Chemical Structure| 1257213-50-5

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MS-986020 (AM152) is a high-affinity lysophosphatidic acid receptor 1 (LPA1) antagonist. BMS-986020 inhibits bile acid and phospholipid transporters, inhibiting BSEP, MRP4, and MDR3, with IC50 values of 4.8 μM, 6.2 μM, and 7.5 μM, respectively. BMS-986020 has potential for research in idiopathic pulmonary fibrosis (IPF).

Synonyms: AM152; AM-000152; AP-3152 free acid

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Product Details of BMS-986020

CAS No. :1257213-50-5
Formula : C29H26N2O5
M.W : 482.53
SMILES Code : O=C(C1(C2=CC=C(C3=CC=C(C4=C(NC(O[C@@H](C5=CC=CC=C5)C)=O)C(C)=NO4)C=C3)C=C2)CC1)O
Synonyms :
AM152; AM-000152; AP-3152 free acid
MDL No. :MFCD30489743
InChI Key :GQBRZBHEPUQRPL-LJQANCHMSA-N
Pubchem ID :49792850

Safety of BMS-986020

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of BMS-986020

GPCR

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.07mL

0.41mL

0.21mL

10.36mL

2.07mL

1.04mL

20.72mL

4.14mL

2.07mL

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