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Chemical Structure| 1256094-31-1 Chemical Structure| 1256094-31-1

Structure of AI-10-47
CAS No.: 1256094-31-1

Chemical Structure| 1256094-31-1

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AI-10-47 is a small molecule inhibitor that disrupts the interaction between CBFβ and RUNX proteins, with an IC50 of 3.2 μM. By inhibiting this interaction, AI-10-47 prevents RUNX-driven cancers, such as acute myeloid leukemia (AML), from proliferating.

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Product Details of AI-10-47

CAS No. :1256094-31-1
Formula : C13H8F3N3O
M.W : 279.22
SMILES Code : FC(F)(F)OC1=CC=C2N=C(C3=NC=CC=C3)NC2=C1
MDL No. :MFCD34167535
InChI Key :JSNWHSDKJSOXET-UHFFFAOYSA-N
Pubchem ID :49804932

Safety of AI-10-47

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.58mL

0.72mL

0.36mL

17.91mL

3.58mL

1.79mL

35.81mL

7.16mL

3.58mL

 

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