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Chemical Structure| 98645-43-3 Chemical Structure| 98645-43-3

Structure of 98645-43-3

Chemical Structure| 98645-43-3

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Product Details of [ 98645-43-3 ]

CAS No. :98645-43-3
Formula : C7H5ClN2O
M.W : 168.58
SMILES Code : N#CC1=C(Cl)N=CC=C1OC
MDL No. :MFCD00975444
InChI Key :MOKUXMQJIYHZCA-UHFFFAOYSA-N
Pubchem ID :1470930

Safety of [ 98645-43-3 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301+H311+H331-H315-H319
Precautionary Statements:P261-P264-P270-P271-P280-P301+P310+P330-P302+P352+P312+P361+P364-P304+P340+P311-P305+P351+P338+P337+P313-P403+P233-P405-P501
Class:6.1
UN#:2811
Packing Group:

Application In Synthesis of [ 98645-43-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 98645-43-3 ]

[ 98645-43-3 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 21642-98-8 ]
  • [ 98645-43-3 ]
YieldReaction ConditionsOperation in experiment
78% With trichlorophosphate; In water; for 2.0h; (107a) 2-chloro-4-methoxynicotinonitrile; A phosphorus oxychloride (10 mL) solution of <strong>[21642-98-8]4-methoxy-2-oxo-1,2-dihydropyridine-3-carbonitrile</strong> (1.50 g, 10 mmol) which was synthesized by a method of Ogawa et al. (Heterocycles, 36,145-148,1993) was heated under reflux for two hours. The reaction liquid was concentrated and a sodium hydrogen carbonate aqueous solution (10 mL) added to the obtained residual substance and the mixture was extracted with ethyl acetate (3x10 mL), and the solvent was evaporated under reduced pressure after the extract was dried over sodium sulfate. The obtained residue was powderized with ether and the title compound was obtained (1.31 g, yield 78percent). Pale yellow powder 1H NMR(DMSO-d6, 400 MHz) delta 4.05 (3H, s), 7.40 (1H, d, J = 4.3 Hz), 8.55 (1H, d, J = 4.3 Hz).
  • 2
  • [ 67-56-1 ]
  • [ 180995-12-4 ]
  • [ 98645-43-3 ]
 

Historical Records

Technical Information

Categories

Related Functional Groups of
[ 98645-43-3 ]

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Related Parent Nucleus of
[ 98645-43-3 ]

Pyridines

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