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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
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Chemical Structure| 98436-74-9 Chemical Structure| 98436-74-9

Structure of 98436-74-9

Chemical Structure| 98436-74-9

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Product Details of [ 98436-74-9 ]

CAS No. :98436-74-9
Formula : C8H6N2
M.W : 130.15
SMILES Code : N#CC1=CC=NC(C=C)=C1
MDL No. :MFCD18820817

Safety of [ 98436-74-9 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H331
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P310-P330-P361-P403+P233-P405-P501
Class:6.1
UN#:3439
Packing Group:

Application In Synthesis of [ 98436-74-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 98436-74-9 ]

[ 98436-74-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 10386-27-3 ]
  • [ 75927-49-0 ]
  • [ 98436-74-9 ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate;palladium diacetate; triphenylphosphine; In 1,4-dioxane; at 85℃; for 4h;Inert atmosphere; Example A3. General experimental for the Suzuki coupling of aryl bromides or chlorides with boronic acidsGeneral Scheme:K2C03, Pd(OAc)2 Ph3P, dioxaneRepresentative SchePh3P, dioxaneA solution of the aryl bromide or aryl chloride (e.g., 6-bromonicotinonitrile, 1 equiv), 4,4,5,5-tetramethyl -2-vinyl-l,3,2- dioxaborolane (2 equiv), K2C03 (2 equiv), Pd(AcO)2 (0.4 equiv) and PI13P (0.8 equiv) in 1,4-dioxane was stirred under N2 at 85 °C until the reaction was complete (approximately 4 h). After cooling to room temperature, the mixture was quenched with water (50 mL) and extracted with ethyl acetate (3 x 50 mL). The combined organic layers were dried over Na2S04 and concentrated under reduced pressure. The crude vinyl-containing product (e.g., 2-vinylisonicotinonitrile) was purified by silica gel chromatography.
 

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