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Chemical Structure| 98135-38-7 Chemical Structure| 98135-38-7

Structure of 98135-38-7

Chemical Structure| 98135-38-7

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Product Details of [ 98135-38-7 ]

CAS No. :98135-38-7
Formula : C6H8N4O
M.W : 152.15
SMILES Code : O=C(C1=NC=CN=C1NC)N

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Application In Synthesis of [ 98135-38-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 98135-38-7 ]

[ 98135-38-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 21279-62-9 ]
  • [ 74-89-5 ]
  • [ 98135-38-7 ]
YieldReaction ConditionsOperation in experiment
61.4% With pyridine; In methanol; at 140℃; for 0.5h;Microwave irradiation; General procedure: The starting compound (1.27 mmol) was treated with 18 aliphatic amines, alicyclic amines or saturated heterocycles containing at least one nitrogen atom (2.54 mmol). Four reactions were completed by conventional heating methods. The conditions were 110 C, toluene as a solvent and pyridine (1.27 mmol) as a base. The reaction time was set to one hour. Then the reactions were completed using the microwave reactor with focused field and conditions used for syntheses were 140 C, 30 min,120 W, methanol used as a solvent and pyridine (1.27 mmol) as a base. They were set experimentally with respect to prior experience. The progress of reaction was monitored with TLC in system hexane/ethyl acetate (1:1). Then the mixture was separated by flash column chromatograph using gradient elution. Mobile phases were hexane and ethyl acetate again.
 

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