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Chemical Structure| 96921-35-6 Chemical Structure| 96921-35-6

Structure of 96921-35-6

Chemical Structure| 96921-35-6

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Product Details of [ 96921-35-6 ]

CAS No. :96921-35-6
Formula : C12H16N2O3
M.W : 236.27
SMILES Code : CC(N1CCOCC1)C2=CC=C([N+]([O-])=O)C=C2

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Application In Synthesis of [ 96921-35-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 96921-35-6 ]

[ 96921-35-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 110-91-8 ]
  • [ 19935-81-0 ]
  • [ 96921-35-6 ]
YieldReaction ConditionsOperation in experiment
95% With potassium carbonate; In DMF (N,N-dimethyl-formamide); at 20℃; for 16.0h; A mixture of 1-(1-bromo-ethyl)-4-nitro-benzene (1.24 g, 5.43 mmol), potassium carbonate (2.25 g, 16.3 mmol) and morpholine (1.2 mL, 13.6 mmol) in DMF (10 mL) was stirred at room temperature for 16h, then evaporated. The residue was suspended in ethyl acetate, washed with water and brine, dried (sodium sulfate) and evaporated to provide 4-[1-(4-nitro-phenyl)-ethyl]-morpholine (1.225 g, 95% yield) as a yellow oil. 1H-NMR (DMSO-d6, 500 MHz) 8.19 (d, 2H), 7.16 (d, 2H), 3.56 (m, 5H), 2.41 (m, 2H), 2.26 (m, 2H), 1.29 (d, 3H) ppm; MS (FIA) 237.2 (M+H); HPLC (Method A) 2.248 min.
 

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